Homework Answers
The G-protein coupled receptors or GPCR are membrane bound receptor proteins which span the plasma membrane nearly 7 times. According to the information, if the plasma membrane is considered to be 4 inches in diameter, the length of GPCR will be at least 7*4 = 28 inch. Thus, the protein structure is very large and an increase in surface area is achieved by multiple foldings of the secondary structure.
This large size of the protein can be compared to more than a feet long scale, such as larger than the size of a shoe-box.
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Question 6 You and your G-protein coupled receptors o You have encountered G-protein coupled receptors in...
The nicotinic acetylcholine receptors are transmembrane protein found in the plasma membrane of human neurons. You...
The nicotinic acetylcholine receptors are transmembrane protein found in the plasma membrane of human neurons. You are studying a member of the receptor family that is glycosylated. Based on this information, answer the following questions: Was the receptor synthesized on cytosolic ribosomes or ER-bound ribosomes? Justify your answer Describe the cellular path that the receptor likely took from synthesis to the plasma membrane.
A. B. C. D. E. F. Thank you receptors induce activation of adenlyate cyclase, which creates...
A. B. C. D. E. F. Thank you
receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
GTP-coupled receptors bind and interact with intracellular proteins. These proteins, in turn, each have a specific...
GTP-coupled receptors bind and interact with intracellular proteins. These proteins, in turn, each have a specific response in cell signaling. Place the description on the correct location of GPCR signaling. 1st attempt See Hint Plasma membrane GDP GDP GTP GDP leaves and exchanges with GTP, leading to subunit dissociation Ligand occupancy of receptor causes a twist in the transmembran e loops, opening the GTP/GDP pocket of the alpha subunit Inactive heterotrimeric G protein bound to GDP Beta/gamma subunits remain as...
22. Steroids bind receptors that are a. Located in the cytoplasm b. G protein-coupled c. Integral...
22. Steroids bind receptors that are a. Located in the cytoplasm b. G protein-coupled c. Integral membrane proteins d. Peripheral membrane proteins 23. Which of the following is the sequence of events in cortisol signaling? a. Gene expression, release of the inhibitor from the receptor, binding of ligand, exposure of DNA binding site, change in conformation of receptor b. Binding of ligand, exposure of DNA binding site, change in conformation of receptor, release of inhibitor from receptor, gene expression c....
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15: GABAB receptors (GABABRs) are G-protein-coupled receptors that can be...
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15:
GABAB receptors (GABABRs) are
G-protein-coupled receptors that can be found on both pre- and
postsynaptic neurons. When they are activated by GABA, they can
have a range of effects. For the synapse you are studying in the
following questions, the effects of GABABRs are
indicated in IMAGE G.
You are doing a series of experiments in which you are recording
from the pre- and postsynaptic cell at a synapse. The experiments
described below...
If you only need to have a small amount of a ligand available to have it...
If you only need to have a small amount of a ligand available to have it bind to a receptor and activate it, we would say that ligand has a _________ for that receptor. For example, when glucocorticoid levels are low, they bind to mineralocorticoid receptors (MR) first because they have a ___________ for glucocorticoids, whereas it takes a higher concentration of glucocorticoids to have them bind to glucocorticoid receptors (GR). GRs are g-protein coupled receptors, and we know that...
Help with these bio questions please.Thank you 1 Secretory protein leave the cell by b Exoctossthey...
Help with these bio questions please.Thank you
1 Secretory protein leave the cell by b Exoctossthey remain in the cytoplasm c) pinocytosis d) receptor mediated 2 If proteins lack a c) Ras d) Signal-recognition particle b) Sorting signal 3 What purpose does the protein coat serve a) Capture molecules to remain in the cytosol b) Shapes the membrane into a phospholipid bilayer membrane c) Provides extra protection and support to the organelles d) none of these are correct cells response...
QUESTION 1 AGº for the hydrolysis of ATP is considered to be: O highly endergonic O...
QUESTION 1 AGº for the hydrolysis of ATP is considered to be: O highly endergonic O highly exergonic O slightly endergonic O slightly exergonic QUESTION 2 Which of the following most closely approximates a second messenger? An odorant receptor on the surface of a mouse olfactory epithelium cell that undergoes a o conformational change upon binding of metabolites (breakdown products) of thyroid hormones, activating an intracellular G-protein. Ca=ions flowing into the cytoplasm and there binding to a protein on the...
n 13 You have found a mutant that has a G-protein that can only bind GDP...
n 13 You have found a mutant that has a G-protein that can only bind GDP and cannot bind GTP. Which of the following might you expect in the mutant cells? red ed out of ag question Select one: a. The secondary messenger would be made constantly. b. The cells would have more energy availability due to higher GTP binding. c. The secondary messenger would not be made. O d. The primary messenger would not be able to bind to...
A. B. C. D. E. F. Thank you
receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
GTP-coupled receptors bind and interact with intracellular proteins. These proteins, in turn, each have a specific response in cell signaling. Place the description on the correct location of GPCR signaling. 1st attempt See Hint Plasma membrane GDP GDP GTP GDP leaves and exchanges with GTP, leading to subunit dissociation Ligand occupancy of receptor causes a twist in the transmembran e loops, opening the GTP/GDP pocket of the alpha subunit Inactive heterotrimeric G protein bound to GDP Beta/gamma subunits remain as...
22. Steroids bind receptors that are a. Located in the cytoplasm b. G protein-coupled c. Integral membrane proteins d. Peripheral membrane proteins 23. Which of the following is the sequence of events in cortisol signaling? a. Gene expression, release of the inhibitor from the receptor, binding of ligand, exposure of DNA binding site, change in conformation of receptor b. Binding of ligand, exposure of DNA binding site, change in conformation of receptor, release of inhibitor from receptor, gene expression c....
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15:
GABAB receptors (GABABRs) are
G-protein-coupled receptors that can be found on both pre- and
postsynaptic neurons. When they are activated by GABA, they can
have a range of effects. For the synapse you are studying in the
following questions, the effects of GABABRs are
indicated in IMAGE G.
You are doing a series of experiments in which you are recording
from the pre- and postsynaptic cell at a synapse. The experiments
described below...
Help with these bio questions please.Thank you
1 Secretory protein leave the cell by b Exoctossthey remain in the cytoplasm c) pinocytosis d) receptor mediated 2 If proteins lack a c) Ras d) Signal-recognition particle b) Sorting signal 3 What purpose does the protein coat serve a) Capture molecules to remain in the cytosol b) Shapes the membrane into a phospholipid bilayer membrane c) Provides extra protection and support to the organelles d) none of these are correct cells response...
QUESTION 1 AGº for the hydrolysis of ATP is considered to be: O highly endergonic O highly exergonic O slightly endergonic O slightly exergonic QUESTION 2 Which of the following most closely approximates a second messenger? An odorant receptor on the surface of a mouse olfactory epithelium cell that undergoes a o conformational change upon binding of metabolites (breakdown products) of thyroid hormones, activating an intracellular G-protein. Ca=ions flowing into the cytoplasm and there binding to a protein on the...
n 13 You have found a mutant that has a G-protein that can only bind GDP and cannot bind GTP. Which of the following might you expect in the mutant cells? red ed out of ag question Select one: a. The secondary messenger would be made constantly. b. The cells would have more energy availability due to higher GTP binding. c. The secondary messenger would not be made. O d. The primary messenger would not be able to bind to...
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