1)B) Exocytosis
Exocytosis – fusion with the cell membrane. Thus lumenal
proteins are secreted extracellularly, and the membrane proteins
will become cell membrane proteins.
Secretory vesicles – these stick around as vesicles in the cell
until needed – where ‘needed’ means they do eventually undergo
exocytosis. In neurons, this is where neurotransmitters are stored
until an action potential demands their secretion into the synapse.
In the stomach, the cells that produce gastric enzymes keep those
enzymes in secretory vesicles until food intake triggers their
release into the stomach.
2)a)Protein Translocator
. The signal recognition particle brings the ribosome to the
endoplasmic reticulum membrane where it interacts with a specific
receptor—the signal recognition particle receptor (or the docking
protein). This interaction directs the polypeptide chain to a
protein translocator. Once this has occurred the signal recognition
particle, and its receptor is no longer required and is released.
Protein synthesis now continues; and, as the polypeptide continues
to grow, it threads its way through the membrane via the protein
translocator, which acts as a channel allowing hydrophilic
stretches of the polypeptide chain to cross.
3)b)Shapes the membrane into a phospholipid bilayer membrane
Cytoplasmic vesicle encapsulated by a protein coat. There are
two types of coated vesicles, coated by coatamer and clathrin,
respectively.
Coatamer: protein complex that encapsulates one class of coated
vesicle. Formation of the coatamer coat on a previously flat
membrane forces the membrane into a curved shape and therefore
drives vesicle formation.
Clathrin: a protein that functions to cause vesicle budding in
response to binding of specific ligand.
4)c) Does not involve gene expression and synthesis of a new
protein.(fast cell response)
Example of a slow process:- Involves a change in gene expression to
make a new protein.
Help with these bio questions please.Thank you 1 Secretory protein leave the cell by b Exoctossthey...
41-50 41. inactwate ơmbinding proteins by converting GTP into GDP -_-- b GTPase 42. What do all GPCR have in common? a. All Participate in mating rituals of single celled yeasts b. All are lipids c. All are carbohydrates d. All pass through the membrane seven times 43. Ras is active when it is bound to GDP b. Fase 44. Ras is activated when it is bound to C. GTP d. GDP 45. Cytoplasmic Ca+ concentration is high in an...
The series of molecules that are activated form a signalling pathway (Figure 3). Central to the signaling pathway are molecules known as kinases and phosphatases. Protein kinases are molecules that catalyze the addition of phosphate groups to proteins there by activating them. Primarily they add phosphate to either tyrosine residues or serine and threonine residues in proteins. Phosphates are molecules that remove a phosphate group from a protein there by de-activating the protein and resulting in shutting down of the...
Hgs is a major target of the Ire1-dependent RNA decay pathway. Mutation of a particular stem-loop sequence in the Hgs mRNA abolishes its degradation during ER stress. What would you conclude from this result? the stem-loop is necessary and sufficient for degradation the stem-loop is sufficient for degradation the stem-loop is necessary but not sufficient for degradation the stem-loop is necessary for degradation Which of the following processes is most likely to be affected by lysosome localization/positioning in the cell?...
Which one of the following statements is false? a. Many growth factor receptors are tyrosine kinases. b. SH2 is an example of a protein domain that has high affinity binding for phosphorylated EGFR. c. Raf initiates a serine/threonine kinase cascade. d. Raf is activated by the kinase activity of RAS. Which one of the following statements is true? a. Retroviruses are a major cause of human cancers. b. Proto-oncogenes are altered forms of normal genes. c. Oncogenic activation of receptor...
1. You are interested in how cyclic-AMP-dependent protein kinase A (PKA) functions to affect learning and memory, and you decide to study its function in the brain. It is known that, in the cells you are studying, PKA works via a signal transduction pathway like the one depicted in Figure 16-15. Furthermore, it is also known that activated PKA phosphorylates the transcriptional regulator called Nerd that then activates transcription of the gene Brainy. Which, if any of the situations described...
Easy questions, 30 min timed assignment, please answer ASAP thanks. The amino acid least likely to be involved in nucleophilic a. Alanine. b. Asparagine. 1. and/or electrophilic enzyme catalysis is e. All are equally likely c. Aspartate. d. Arginine Fibrous proteins, such as collagen, have which one of the following properties? a. b. c. d. e. 2. highly soluble in water their hydrophilic residues are directed into the interior of the protein exhibits enzymatic activity serve structural roles in the...
A8. Which of the following describes carbohydrates? (a) a base, a sugar, and a phosphate b) aldchydes and ketones with two or more hydroxyl groups. c) acids with two or more hydroxyl groups. d) amines with two or more hydroxyl groups. e) always contain a phosphate group. A9. Which of the following is NOT correct regarding reducing sugars? a) Sugars that react with oxidizing agents are called reducing sugars. b) The cyclic form of a monosaccharide reacts with oxidizing agents....
6. Lipid-soluble signaling molecules, such as testosterone, cross the plasma membranes of all cells A) by diffusion but affect only target cells because only target cells retain the appropriate DNA segments. B) by diffusion but affect only target cells because only target cells have the intracellular receptors for testosterone. C) through hydrophilic channels of transmembrane proteins but affect only target cells because only target cells retain the appropriate DNA segments. D) through hydrophilic channels of transmembrane proteins but affect only...
3. Label the following statements about the unfolded protein response (UPR) as either true or false. If it is FALSE, explain why it is false. a. Activation of the UPR results in the production of more ER membrane. b. Activation of the UPR results in the production of more chaperone proteins. c. Activation of the UPR occurs when receptors in the cytoplasm sense misfolded proteins. d. Activation of the UPR results in the cytoplasmic activation of gene regulatory proteins.
Please answer all questions 2 After isolating the rough endoplasmic reticulum from the rest of the cytoplasm, you purify the RNAS attached to it. Which of the following proteins do you expect the RNA from the rough endoplasmic reticulum to encode? (a) (c) soluble secreted proteins plasma membrane proteins ER membrane proteins all of the above (b) (d) -13 In which cellular location would you expect to find ribosomes translating MRNAS that encode ribosomal proteins? (a) (c) the nucleus in...