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D Question 4 A silent mutation has no change in RNA sequence O no change to DNA, RNA, or protein O no change in protein seque

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Answer #1

Question 4

Answer: no change in protein sequence

Explanation: There are certain mutations in the nucleotide sequence that do not change the sequence of amino acids in a protein. For example, suppose the codon CAU gets mutated to CAC. Now, both CAU and CAC code for the amino acid Histidine. Thus, even after the mutation, there occured no change in the amino acid. Such mutations are called silent mutations.

The mutations in DNA sequence get reflected in the RNA sequence as well. Thus the first option is incorrect.

A silent mutation changes the nucleotide sequence although amino acid sequence in a protein remains the same. Thus, the second option is also incorrect.

Silent mutations change the nucleotide sequence in DNA. Thus, the fourth option is also incorrect.

Question 5

Answer: missense mutation

Explanation: Missense mutations are those mutations that change the codon in such a manner that it codes for an entirely different amino acid. For example, when CAU (coding for Histidine) gets mutated to CAG (coding for Glutamine) it is a missense mutation.

Nonsense mutations occur when the mutation changes any codon coding for an amino acid to a stop codon. For example, when UAC (coding for Tyrosine) gets mutated to UAG (stop codon), it is a missense mutation. Thus, the first option is incorrect.

A silent mutation changes the nucleotide sequence although amino acid sequence in a protein remains the same. Thus, the fourth option is also incorrect.

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