Question

11. Match each type of mutation with the corresponding description. (4 points) Missense An insertion or deletion of nucleotides that are not in multiples of 3. Nonsense A mutation that does not alter the protein sequence. Silent A mutation that confers an amino acid substitution. Frameshift A mutation that confers a premature stop codon.

Answer 1

O Missense - A mutation that confens an amino acid substitution. In this midation a single base pour change leads to Substitution of one amino add for another. In the protein subjected to this mutation. This mutation me y or may not be harmful. Nonsense » A mutation that confers a bremature stop codon. In this mutation a codon that codes for an amino add is changed to a termination codon or stop codon. The result is formation of incomplete or shorter protein due to premature introduction of stop or nonsense codon. Silent - A mutation that does not alter protein sequence. In this mutation 1 the substitution of nucleotide does not I lead to change in amino add. For example it AAA changes to AAG - both will code for lysine. (This mutation alters nucleotide at third position). Frameshift » insertion or deletion not in multiples of 3. It is due to insertion of deletion of the di base bairs that lead to change in reading frame es schresulting in completly different proteino CamScanner

(Answens) Missense - (3) Nonsense - (4) Silent - (2) frameshift - (i) - Scanned with CamScanner