Question

Using these types of genetic changes: Base substitution, Transition, Transversion, Missense mutation, Nonsense mutation, Insertion, Deletion,...

Using these types of genetic changes: Base substitution, Transition, Transversion, Missense mutation, Nonsense mutation, Insertion, Deletion, Frameshift mutation

Label these genetic changes (a-e). More than one answer may apply to each answer.

a. GC->CG in the protein coding region on a gene.

b. GC->TA in a GAA glutamate codon

c. Loss of three bases GAA for a glutamate codon

d. GC->CG in a tRNA gene

e. GC->AT in the ribosome binding site of a mRNA

0 0
Add a comment Improve this question Transcribed image text
Answer #1

1 ..Base substitution means

The one amino acid base is substituted by another like A to G , C to A etc

It may cause 3 changes

Protein sequence may change eg in sickle cell anemia

Code is changed but while encording it the protein remain same is silent mutation

Change in codon may lead to sequence of stop codon so the new protein synthesis stops

2. Insertion

Means new base pair is added in it

Eg AAACTCGGG in 3' now become AAACCCTGGG

3.Deletion means

One base pair or sequence is deleted

AAACCGGG from above main sequence one C deleted

4 Frameshift means

Caused by insertion or deletion may cause change in reading codon

5. Nonsense mutation

Convert one base sequence into one of the three non sense codon

6. Missense mutation

Codon changes its sequence so diff amino acid sequence is produced

7 Transition means

Purine base pair replace purine and pyrimidine replace pyrimidine

8 transversion

Purine replaced by pyrimidine and vice versa

Purine is adenine and guanine

Pyrimidine is thymine and cytosine

Uracil in place of thymine in RNA

Answer

1 GC to CG Transversion

2 GC to TA Transversion

3 Deletion

4 GC to CG Transversion

5 GC to AT Transition

Add a comment
Know the answer?
Add Answer to:
Using these types of genetic changes: Base substitution, Transition, Transversion, Missense mutation, Nonsense mutation, Insertion, Deletion,...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • 1. The following is a sequence of RNA. Do you expect it to adopt any kind...

    1. The following is a sequence of RNA. Do you expect it to adopt any kind of structure, and, if so, show what the structure would be? 5'-AUACUGCCCCCGGGGGAUGCCCGUAAACCGGGGUUACCCGGUUUAAACGGCCCCCCGGGGGCAGGCG-3'. 2. A dipoid yeast was ABD on one chromosome and abd on the other. The yeast cell underwent meiosis and the four genomes in the resulting tetrad were analyzed and determined to be: ABD, ABD, ABD and abd. a. For the moment, focus on the outcome regarding the number of B versus...

  • 11. Match each type of mutation with the corresponding description. (4 points) Missense An insertion or...

    11. Match each type of mutation with the corresponding description. (4 points) Missense An insertion or deletion of nucleotides that are not in multiples of 3. Nonsense A mutation that does not alter the protein sequence. Silent A mutation that confers an amino acid substitution. Frameshift A mutation that confers a premature stop codon.

  • Match each mutation with its appropriate description. A mutation that changes a codon that specifies an...

    Match each mutation with its appropriate description. A mutation that changes a codon that specifies an amino acid to a stop codon, resulting in premature termination of polypeptide synthesis. Silent mutation Frameshift mutation A mutation that results in a change in a codon such that a different amino acid is specified es Missense mutation A mutation that changes one codon to a different codon that specifies the same amino acid, such that there is no change in the resulting polypeptide....

  • A single mutation has occurred in the following DNA sequence. 5' ATG TTG GCC CAT 3'...

    A single mutation has occurred in the following DNA sequence. 5' ATG TTG GCC CAT 3' wild-type (normal) sequence 5' ATG TTG CCC CAT 3' mutant sequence    (a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification. (1.75 marks)    (b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you...

  • Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is...

    Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is in, what effect it will have on the protein (e.g. nonsense missense, silent) as well as the amino acid change it will cause if it is a substitution. Refer to the genetic code. U UUU C UCU Uục Phe UCC Ser UUA UUG CUU UCA UCG CCU CCC Α UAU UAC y UGC cys UAA Stop UGA Stop UAG Stop UGG trp CGU CAC"...

  • can someone double check my answers? also, if incorrect can you explain why? For the following...

    can someone double check my answers? also, if incorrect can you explain why? For the following wild-type alle SATG GAC TOG GTA ACT GAT ATG ATA GIG COC GGG GAA CGC GOGOGG TA 1 write the aminoacide of the w eather or neramino acid abbreviation ) S-UAC CUG ACC CAU UGA CUA VAC UAU CAC GGG CCC CUN GOS CGC GCC AUD See the STOP proletaria 2. Write the amino acide nce of the following mutants: Mutant 1 transition nucleotide...

  • Please answer all.... Thank you! 81)If a polypeptide chain contains 600 amino acids, then the gene...

    Please answer all.... Thank you! 81)If a polypeptide chain contains 600 amino acids, then the gene coding for this polypeptide must contain _____. 600 nucleotides 1200 nucleotides 1800 nucleotides 1800 codons 1800 anticodons More than one of the above are correct. 82) When we altered gene triplet in the DNA produces a chain-terminating codon in the mRNA, the (1pts) result is called a reverse mutation nonsense mutation missense mutation spontaneous mutation frameshift mutation 83) A single base substitution changes the...

  • A cell that is heterozygous for a nonsense mutation in a tumor suppressor gene would most...

    A cell that is heterozygous for a nonsense mutation in a tumor suppressor gene would most likely: A) Group of answer choices B) grow but not divide C) have a normal cell cycle D) arrest and induce apoptosis E) have a slightly increased cell cycle and increased cell growth F) grow and divide uncontrollably Which of the following correctly describes an event that occurs during transcription: Group of answer choices A) A DNA molecule is chemically modified to become a...

  • D) Consider that during replication of the cell. the following mutations were generated within the gene...

    D) Consider that during replication of the cell. the following mutations were generated within the gene sequence. Find the mutation (in bold Italics-underlined Specify the protein sequences for each mutant sequence. mutation type 1: This is a non-sense mutation because the codon does not code for an amino acid any more 5' -..AACTAATGCCGTAAGACGTATTTTGACTAAT..-3' (substitution of a C 7 A in codon 3) 3'- TTGATTACGGCAT ICTGCATAAAACTGATTA..-5 S mutation type 2: This is a missense mutation because the codon now codes for...

  • #1 Mutation 1. A chromosomes has the following segments, where represents the centromere: MNOPQRST Give the...

    #1 Mutation 1. A chromosomes has the following segments, where represents the centromere: MNOPQRST Give the chromosome sequences that would result from the following mutations: a. Deletion of MN Pericentric inversion of NOP C. Inversion of RS, followed by tandem duplication of QRST b. 2. Which type(s) of chromosomal mutations: a. Increase the amount of genetic material in a particular chromosome? b. Increase the amount of genetic material in the entire genome? c. Decrease the amount of genetic material in...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT