A cell that is heterozygous for a nonsense mutation in a tumor suppressor gene would most likely:
A) Group of answer choices
B) grow but not divide
C) have a normal cell cycle
D) arrest and induce apoptosis
E) have a slightly increased cell cycle and increased cell growth
F) grow and divide uncontrollably
Which of the following correctly describes an event that occurs during transcription:
Group of answer choices
A) A DNA molecule is chemically modified to become a protein
B) tRNA molecules pair with codons in the DNA
C) amino acids are linked together
D) RNA polymerase recognizes and binds to the promoter DNA sequence
E) Translation is initiated at the start codon
Which of the following describes a mutation that has the potential to become a germline mutation?
Group of answer choices
A) a deletion of the promoter DNA sequence of a gene in a female gamete
B) All of the possible answers
C) a 2 base-pair DNA deletion that occurs from UV damage in a skin cell
D) a point mutation in the BRCA1 gene caused by an error in DNA replication in a breast epithelial cell
E) a transcription error causing a deletion of two-bases in an mRNA molecule within an egg cell
1) C [have a normal cell cycle]
2) D [RNA polymerase recognizes and binds to the promoter DNA sequence]
3) E [a transcription error causing a deletion of two-bases in an mRNA molecule within an egg cell]
A cell that is heterozygous for a nonsense mutation in a tumor suppressor gene would most...
Question 9 (5 points) An outcome of a mutation in a tumor suppressor gene protein product is ___ 1) cell cycle continues and cell may become cancerous 2) cell cycle stops and the cell tries to repair itself or it undergoes apoptosis - programmed cell death 3) all the above mark
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A gene that inhibits the transition from G1 to S phase c. d. A gene that promotes cell growth, combined with a hyperactive promoter How would methylation of the promoter of the gene in question 3c affect the cell? Be specific using what you know about the...
Consider a spontaneous mutation in the gene HER2, a tumor suppressor involved in cell cycle control Mutations happen at a rate of about 1 error per 109 bases per generation. A spontaneous deleterious mutation must occur in HER2 specifically, and not in another gene. The likelihood that a spontaneous mutation is deleterious and could lead to cancer depends on the number of mutable bases in HER2, the fraction of bases that will affect the function of HER2, and that both...
1.The KRAS gene encodes the KRAS protein which functions to promote cell growth and division. A single base-pair deletion occurs in exon 4 of the KRAS gene that results in an early stop codon. This mutation results in an unregulated KRAS protein that always sends growth signals. What is a correct classification of the normal (wildtype) KRAS gene? A) A tumor suppressor gene B) An oncogene C) A tumor activating gene D) A DNA repair gene E) A proto-oncogene 2....
Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene? Given that is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without...
M8Q1: Quiz Question 1 "By definition, a gene that can lead to tumorigenesis when over-expressed is_______." Group of answer choices: a. A tumor suppressor gene b. An oncogene c. A transgene d. A virus Question 2 A tumor suppressor gene is typically____________ Group of answer choices: a. "A gain of function, dominant mutation" b. "A gain of function, recessive mutation" c. "A loss of function, dominant mutation" d. "A loss of function, recessive mutation" Question 3 Cyclins regulate______________. Group of...
11. Deoxyribose 12. 13. 14. 15. 16. Nucleus Point mutation Deletion mutation Exons Translation Nitrogenous bases H bonded mRNA A. Molecule that carries instructions for making a protein from a gene in the nucleus to a ribosome in the cytoplasm B. Enzyme that unwinds DNA double helix C. Sugar found in DNA nucleotide D. Process of making a protein E. Substitution of one nucleotide base pair for another F. Rungs (steps) of DNA "ladder" G. Transcription occurs in this part...
Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What happens when cells do NOT respond to the cell cycle control system and divide excessively? Tumor Proto-oncogeno (for protein that stimulates coll division) 6 Y DNA Benign Tumor= Mutation withln a control region of DNA Malignant Tumor Mutated promoter Metastasis Normal growth-stimulating protein in excess Oncogene Tumor-Suppressor Genes Proto-oncogene utled tara gese Samor-auppresr gane Many proto-oncogenes code for growth factors /Deletive nonimenig Normel grewt...
Sickle Cell Anemia Sickle cell anemia is the result of a type of mutation in the gene that codes for part of the hemoglobin molecule. Recall that hemoglobin carries oxygen in your red blood cells. The mutation causes these red blood cells to become stiff & sickle-shaped when they release their oxygen. The sickled cells tend to get stuck in blood vessels, causing pain and increased risk of stroke, blindness, damage to the heart & lungs, and other conditions. Analyze...
12. Nucleus 13. Point mutation 14. Deletion mutation 15. Exons 16. Translation 17. Nitrogenous bases H bonded 18. mRNA B. Enzyme that unwinds DNA double helix C. Sugar found in DNA nucleotide D. Process of making a protein E. Substitution of one nucleotide base pair for another F. Rungs (steps) of DNA "ladder" G. Transcription occurs in this part of the cell H. Enzyme that synthesizes DNA by connecting bases tha are complementary to the original template stra 1. Removing...