Question

M8Q1:

Quiz Question 1

"By definition, a gene that can lead to tumorigenesis when over-expressed is_______."

Group of answer choices:

a. A tumor suppressor gene

b. An oncogene

c. A transgene

d. A virus

Question 2

A tumor suppressor gene is typically____________

Group of answer choices:

a. "A gain of function, dominant mutation"

b. "A gain of function, recessive mutation"

c. "A loss of function, dominant mutation"

d. "A loss of function, recessive mutation"

Question 3 Cyclins regulate______________.

Group of answer choices:

a. Translation in the cell

b. Replication in the cell

c. Phosphorylation in the cell

d. Apoptosis in the cell

Question 4

Familial cancers are more prevalent than spontaneous cancers.

Group of answer choices:

a. True

b. False

Question 5

Once Rb is released from E2F

Group of answer choices:

a. Cell cycle progression will occur

b. Cell cycle progression is halted

c. Cells are killed

d. Cells will become tumorous

Question 6

P53 mutations are only found in Li Fraumeni syndrome

Group of answer choices:

a. True

b. False

Question 7

The two-hit hypothesis states that______________.

Group of answer choices:

a. An accumulation of mutations typically leads to cancer

b. Two different alleles must be mutated for cancer to grow

c. Two cells must be mutated for cancer to grow

d. Multiple exposure to viruses leads to tumorigenesis

Question 8

Vaccines currently exist for prevention of cervical cancer.

Group of answer choices:

a. True

b. False

Question 9

Which of the following is characteristic of ALL cancer?

Group of answer choices:

a. Two genetic mutations

b. Metastasis

c. Environmental factors

d. Viral infection

Question 10

Which virus is associated with cervical cancer?

Group of answer choices:

a. Epstein Barr virus

b. Human papilloma virus

c. Influenza virus

d. H1N1 virus

e. Adenovirus

Answer 1

Answer 1) Option B - An oncogene - it is a gene that can potentially cause cancer when over expressed or mutated

tumor suppressor gene (anti oncogene) - is responsible for regulations of cell division and replication. when this gene is mutated cell grows uncontrollably and result in neoplasia.

Due to this mutation which is usually recessive, there is reduction in function.

Transgene - A transgene is a gene transferred from.one organism to other naturally or by artificial means. It is nothing to do with tumor genesis.

Virus -virus is an infectious agent what can only reproduce inside other living cells.

Answer 2) option D loss of function, recessive mutation

answer 3) option C - phosphorylation in the cell

Answer 4) False