Question

RENAL PHYSIOLOGY SIMULATION The tables below represent three different patients who have consumed one of the following test beverages: 1000 mls of distilled water (a hypotonic load) 100 mls of 0.5% NaCl (a hypertonic load) 500 mls of 0.9% NaCl (an isotonic load) The volumes represent the urine output for each patient at 30 minute intervals. Calculate the flow rate over time for each patient to determine which patient consumed which beverage. PATIENT 1 TIME (minutes) VOLUME (ml) FLOW RATE (ml/min) SPECIFIC GRAVITY 0 50 1.017 30 36 1.025 60 24 1.032 90 18 1.035 120 30 1.032 PATIENT 2 FLOW RATE (ml/min) TIME (min) 0 VOLUME (ml) 50 30 60 SPECIFIC GRAVITY 1.017 1.017 1.017 1.017 1.017 60 66 90 48 120 40 PATIENT 3 TIME (min) FLOW RATE (ml/min) VOLUME (ml) 50 75 SPECIFIC GRAVITY 1.017 1.014 0 30 60 178 1.010 1.003 1.010 90 189 120 153

Answer 1

Answer:

Patient 1
The amount voided at 0 time. 50ml is just for reference and not to be included in output
In the first hour the output was 36 + 24 = 60 ml / 1 hr or 60 ml / 60min
In the second hour output was 18 + 30 = 48 ml / 1hr or 48 ml / 60 min
Considering the specific gravity = the specific gravity has increased in the second hour

Patient 2:
The amount voided at 0 time. 50ml is just for reference and not to be included in output
In the first hour the output was 60 + 66 = 126 ml / 1 hr or 126 ml / 60min
In the second hour output was 48 + 40 = 88 ml / 1hr or 88 ml / 60 min
Considering the specific gravity = the specific gravity has remained constant over the two hours

Patient 3:
The amount voided at 0 time. 50ml is just for reference and not to be included in output
In the first hour the output was 75 + 178 = 253 ml / 1 hr or 253 ml / 60min
In the second hour output was 189 + 153 = 342 ml / 1hr or 342 ml / 60 min
Considering the specific gravity = the specific gravity has decreased consistently

From the above data comparisons we can conclude that:
Patient 1 has consumed only 100 ml of 0.5% NaCl,
Patient 2 has consumed only 500 ml of 0.9% NaCl,
Patient 3 has consumed only 1000 ml of Distilled Water