Question

QUESTION 23 Which of the following is true of an individual with a homozygous CCR5 delta-32 mutation: O A. cannot be infected with CXCR4-tropic HIV strains OB. can be more readily infected with HIV than a person with two normal CCRS alleles OC. is more prone to develop AIDS rapidly following HIV infection OD. is unable to be infected with HIV E. is highly resistant to infection with CCRS-tropic HIV strains QUESTION 24 A fusion sequence is: O A highly acidic B. highly hydrophilic C. comprised entirely of lipids D. an integral part of the cell's receptor E. highly hydrophobic

Answer 1

ANSWERS

23- Option D is correct.

• An individual with a homozygous CCR5 delta-32 mutation are unable to be infected with HIV.
• CCR5 delta-32 mutation is an HIV resistant mutation.
• The mutation causes the CCR5 co-receptor on the outside of cells
• CCR5 co-receptor is like door that allows HIV entrance into the cell
• The CCR5-delta 32 mutation locks the door which prevents HIV from entering into the cell.

24- option A IS CORRECT.

• A fusion sequence is highly acidic.