Listed below are four reaction schemes (Scheme A - D), as well
as a synthetic target. Select which scheme will give the desired
product with the greatest selectivity, and briefly describe why
(both need to be included for full credit):
Listed below are four reaction schemes (Scheme A - D), as well as a synthetic target....
QUESTION 11 Listed below are four reaction schemes (Scheme A-D), as well as a synthetic target. Select which scheme will give the desired product with the greatest selectivity, and briefly describe why (both need to be included for full credit): Scheme A Me LDA -78 °C Ph Н. -78 °C to 25 °C 25 °C Scheme B Fo Me LDA 25 °C Ph H 25 °C to -78 °C -78 °C Scheme C Scheme C Me LDA Ph Н. -78...
Listed below are four reaction schemes (Scheme A-D), as well as a synthetic target. Select which scheme will give the desired product with the greatest selectivity, and briefly describe why (both need to be included for full credit): Scheme A Me LDA -78 °C Ph -78°C to 25°C 25°C Scheme B Me LDA 25 °C Ph 25°C to -78 °C -78 °C Scheme C Me LDA Ph H -78 °C -78 °C Scheme D . Me LDA -78 °C 25...
QUESTION 11 Listed below are four reaction schemes (Scheme A 01, as well as a synthetic target Select which scheme will give the desired product with the greatest selectivity and briefly describe why both need to be included for tuli crede Scheme Ne LDA -700 -78C25C25C Scheme Schenec Me LDA . Scheme -100
Show the structure of your target molecule as well as the Synthetic
schemes illustrating the two steps required for preparing it from
“allowed” starting materials. for each synthetics that indicate the
source of the experimental procedure you will follow - sources can
either be literature references or simply the course packet self.
Proposed Synthesis Show the structure of your target molecule as well as synthetic schemes illustrating the two steps required for preparing it from "allowed" starting materials. For each...
Proposed Synthesis Show the structure of your target molecule as well as synthetic schemes illustrating the two steps required for preparing it from "allowed" starting materials. For each synthetic step indicate the source of the experimental procedure you will follow-sources can either be literature references or simply the course pack itself. (See the example below for the format to be followed) ~Example Target Molecule: NO2 Cl Step 1: OH Reference: Tetrahedron, 1990, 46, 2975 HNO3 Step 2 o H2SO4 NO2...
Indicate the reaction in the sequence below that wouldn't work (i.e. is a synthetic trap) and briefly explain why. H.CO. LDA -78 "C yay 2. H.0 BIŲ A A - I 3 x x - Vedete cu o 12pt HTML Editon E Paragra
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
**(left structure)****(right
structure)**
The two structures for the assignment are above and
the task is:
1. Perform a retrosynthetic analysis on the two target
molecules assigned to you. In each case the organic
starting material (what you have to work backwards toward) depends
upon the target. For the structure given above (structure on left),
the starting material is either malonic ester or acetoacetic ester
and any halide. For the structure given above (structure on right),
the starting material is any...
Propose an efficient synthesis for the transformation below,
using two sequential reductive aminations. Enter
the appropriate number or letter from the reagent list handout.
Propose an efficient synthesis for the transformation below, using two sequential reductive aminations. Enter the appropriate number or letter from the reagent list handout. Step 1 + NaBH3CN, H+, Step 2 - NaBH3CN, H+ Reagent List (Updated 4/30/2020) Enter # or letter in the appropriate boxes. Note: Exam responses are case insensitive Alkyl Halides (X = Cl,...