Homework Answers
Hope you and your family are well in this pandemic. The question
asked by you is a famous question from Medicinal organic chemistry.
The molecule is containing free -OH and -NH2 groups. So,
these two groups are responsible for the reactions occuring in
metabolism phase-II reactions.
The reactions are-
4.
5. Methylation of Amino group
RNH2 ------> RNHMe
Enzyme: Methyl transferase
These are the 5 reactions which the drug will carry out.
Add Answer to:
What is the metabolism phase2 reactions that (acyclovir) can
react? Write them all
NH2 ОН: -N...
What is the metabolism phase 1 reactions that (acyclovir) can react? Write them all NH2 ОН:...
What is the metabolism phase 1 reactions that (acyclovir) can
react? Write them all
NH2 ОН: -N NH N
What is the metabolism phase 1 reactions that (acyclovir) can react? Write them all NH2 ОН:...
What is the metabolism phase 1 reactions that (acyclovir) can
react? Write them all
NH2 ОН: -N NH N
What is the metabolism phase 2 reactions that (acyclovir) can Undergo ? Write all chemical reactions...
What is the metabolism phase 2 reactions that (acyclovir) can
Undergo ? Write all chemical reactions (structures)
Medical chemistry
NH2 ОН: -N NH N
Use principle of bioisoterism, Get 10 analogues of ( Acyclovir) NH2 ОН: -N NH N Show...
Use principle of bioisoterism,
Get 10 analogues of ( Acyclovir)
NH2 ОН: -N NH N
Use principle of bioisoterism, Get 10 analogues of ( Acyclovir) With smiles notation and properties NH2...
Use principle of bioisoterism,
Get 10 analogues of ( Acyclovir)
With smiles notation and properties
NH2 ОН: -N NH N
Classify the following reactions. Explain your choices. + CO2 NH2 ATP NH2 NH он + O...
Classify the following reactions. Explain your choices.
+ CO2 NH2 ATP NH2 NH он + O R2 NH 0 0 0 0 0 NH glutathione NH 0 OH OH O OH HO он OH OH OH OH glucose-6-phosphate fructose-6-phosphate HO он cis-aconitic acid isocitric acid OH 8.
following reactions. If reagents are added in separate steps, don't forget to number them. NH2 OH...
following reactions. If reagents are added in separate steps, don't forget to number them. NH2 OH он NH b) 1) NaOCH2CHs H2CHs 2) neutralize (add second) c) 1. NaCN 2. LiAIH4 3. H20 d) NaOH OH он HN 1) excess CH3CH2MgBr 2) neutralize
can you name these compounds? он NH2 2 NH2 4 3 5. снз 8. 7 но...
can
you name these compounds?
он NH2 2 NH2 4 3 5. снз 8. 7 но 10 OH NH CH3 сHS 13 14 Но
provide the mechanism of the following reductive amination NH2 H₂N |—NH HN- ОН Amberlyst 15 Ethanol,...
provide the mechanism of the following reductive
amination
NH2 H₂N |—NH HN- ОН Amberlyst 15 Ethanol, NaBHA OH HO Unknown Carbonyl Compound (2 equivalents)
provide the major product in the following reactions ОН TsCI O Et N NH2 1. CHg-Br (xs) 2. Ag2O, H20, A H-CI Et20
provide the major product in the following reactions
ОН TsCI O Et N NH2 1. CHg-Br (xs) 2. Ag2O, H20, A H-CI Et20
What is the metabolism phase 1 reactions that (acyclovir) can
react? Write them all
NH2 ОН: -N NH N
What is the metabolism phase 1 reactions that (acyclovir) can
react? Write them all
NH2 ОН: -N NH N
What is the metabolism phase 2 reactions that (acyclovir) can
Undergo ? Write all chemical reactions (structures)
Medical chemistry
NH2 ОН: -N NH N
Use principle of bioisoterism,
Get 10 analogues of ( Acyclovir)
NH2 ОН: -N NH N
Use principle of bioisoterism,
Get 10 analogues of ( Acyclovir)
With smiles notation and properties
NH2 ОН: -N NH N
Classify the following reactions. Explain your choices.
+ CO2 NH2 ATP NH2 NH он + O R2 NH 0 0 0 0 0 NH glutathione NH 0 OH OH O OH HO он OH OH OH OH glucose-6-phosphate fructose-6-phosphate HO он cis-aconitic acid isocitric acid OH 8.
following reactions. If reagents are added in separate steps, don't forget to number them. NH2 OH он NH b) 1) NaOCH2CHs H2CHs 2) neutralize (add second) c) 1. NaCN 2. LiAIH4 3. H20 d) NaOH OH он HN 1) excess CH3CH2MgBr 2) neutralize
can
you name these compounds?
он NH2 2 NH2 4 3 5. снз 8. 7 но 10 OH NH CH3 сHS 13 14 Но
provide the mechanism of the following reductive
amination
NH2 H₂N |—NH HN- ОН Amberlyst 15 Ethanol, NaBHA OH HO Unknown Carbonyl Compound (2 equivalents)
provide the major product in the following reactions
ОН TsCI O Et N NH2 1. CHg-Br (xs) 2. Ag2O, H20, A H-CI Et20
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