Question
What is the metabolism phase2 reactions that (acyclovir) can react? Write them all
NH2 ОН: -N NH N
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Answer #1

Hope you and your family are well in this pandemic. The question asked by you is a famous question from Medicinal organic chemistry. The molecule is containing free -OH and -NH2 groups. So, these two groups are responsible for the reactions occuring in metabolism phase-II reactions.
The reactions are-

4.

5. Methylation of Amino group

RNH2 ------> RNHMe

Enzyme: Methyl transferase

These are the 5 reactions which the drug will carry out.

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