Answers are 2 and 3 ( ligands and drugs)
Ligand-gated ion channels opens when ligand binds to receptor site.
Specific drugs like neurotransmitters regulates the opening of these channels.
Movement of ions is regulated by specific drugs and ligands.
Although the ligand-gated ion are ion channels they are considered to be receptors as they only...
Receptors that bind IP3 are generally metabotropic receptors GPCRs receptor tyrosine kinases ligand-gated ion channels
1) Which ligand-gated ion channels does (glutamate / GABA / glycine) open? 2) How do changes in (potassium / sodium) concentration affect the resting membrane potential? 3) If (sodium / potassium / chloride) channels are locked open, the membrane potential will continue to change due to ion flow until it reaches what value? (give a numerical value)
Select the fundamental properties of all ion channels. ligand‑gated rapid transport use active transport selectivity
A. B. C. D. E. F. Thank you receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...
choices for A: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels choices for B: bidirectionally, unidirectionally choices for C: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels choices for D: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels Consider this graph illustrating the generation of an action potential across the plasma membrane of a stimulated neuron. +40 ACTION POTENTIAL plasma membrane potential...
Six molecular targets for drugs where described. Pick 3 of these targets and complete the table for each target. (Molecular target, Pharmacodynamics, Clinical Pharmacology, and list 10 different drugs for the given molecular target). Also pharmacodynamics and clinical pharmacology based upon the molecular target please. The easy molecular targets that I picked where Membrane receptors (G protein-coupled receptors, target of 50% of drugs), enzymes (especially protein kinases, proteases, esterases, and phosphatases), and ion channels (ligand-gated ion channels, voltage-gated ion channels)
1. In paracrine signaling, the signaling molecules affects only: Target cells close to the cell from which it was secreted a. b. Target cells distant from its site of synthesis in cells of an endocrine organ Both a. and b. с. d. None of these 2. Below are listed the events that occur in cell to cell communication. Signal transduction occurs 1. 2. Plasma membrane receptor binds with a ligand A cellular response is effected 3. 4. Ligand is released...
Assume a mutation of the gene coding for the voltage-gated sodium channel resulted in channels that do not have the ball and chain part of the protein. Which of the following would you expect to see? a. A change in the ion selectivity of the channel of the mutated channels, allowing ions other than sodium to move through it. b. A change in the voltage sensitivity of the channel so that it does not open until more depolarized voltages. c....
Voltage-gated Na channels exist in three distinct conformations in axons because Answers A-D A they assume an inactivated conformation shortly after opening, which ensures that the action potential cannot move backwards toward the cell body. B they change conformation when binding Nat and transporting it to the opposite side of the membrane before releasing it outside the cell. C they respond to ligand binding, mechanical stress, or changes in voltage. D they assume different conformations as ATP is bound and...
Which of the following describe or exemplify metabolotrophic receptors (select all that apply)? Select one or more: a. Protein channels opening and allowing neurotransmitters or ions to flow into the cell b. Salty taste receptor c. Signal transduction cascades that can lead to depolarization events d. Bitter taste receptors e. Internal g-proteins activated by binding of a stimulus or ligand on the cell’s exterior