Question

What are characteristics of the pedigrees of families with mitochondrial diseases? Multiple Choice Only the male children of affected mothers are affected, female children are not affected, All children of affected males are usually affected. All children of affected mothers are usually affected regardless of their sex. Only female children of affected mothers are also affected, male children are not affected.

Answer 1

Mitochondrial inheritance is also known as cytoplasmic inheritance. The mother passes the genes present in motochondria to all offspring.

If the mother is affected by the trait, then all offsprings are affected whether the sex is son or daughter.

Answer is: option 3.

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Allelic frequency of B : genotypic frequency of BB + (1/2) ×Bb= (1600/10000) + (1/2) ×(4800/10000) = 0.16+ (1/2) × 0.48= 0.16+ 0.24= 0.40

Allelic frequency of b is 1- B= 1-0.40=0.60

Expected individuals:

BB= (B) ^2 ×10, 000= (0.40) ^2 ×10, 000= 16,00

Bb= 2×B×b×10, 000= 2×0.40×0.60×10, 000= 48,00

bb=(b}^2×10,000= (0.60) ^2×10, 000= 36,00

There are not found significant difference between observed and expected number. That's why population is in Hardy Weinberg equilibrium.

Answer is : True.

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