Question

D Question 16 Identify a FALSE statement about imprinting a) Nuclear transfer experiments using pronuclear stage embryos showed that reconstituted embryos with two maternal genomes never survive beyond mid-gestation b) Imprinted alleles are expressed only from the imprinted allele inherited from the mother or from the imprinted allele inherited from the father One mechanism involved in maintaining imprinting is DNA methylation d) Imprinting is removed during germ cell development in the fetus. e) Imprinting genes are maintained throughout mitotic cell divisions in the somatic cells of an organism,

Answer 1

The genomic imprinted is removed during the germ cell development and is only maintained by the somatic cells during the mitotic cell division. The process of DNA methylation is important for the genomic imprinting. For a cell to have imprinting it must inherit the parents imprinted genome to fully express the imprinting. A cell having two maternal genomes can develop normally with a small trophoblast and yolk sac.

The answer is A.