Give the additional reactants (ester, ketone, etc.) AND appropriate base required to form the products for...
Give the additional reactants (ester, ketone, etc.) AND appropriate base required to form the products for the reactions below lor. S olo
give reactants, reagents, and/or products for the following reactions, as appropriate. reactants, reagents, and/or products for the following reactions, as appropriate SOCI dom OH 1) NaBH, (excess) SOCIE OCH 2) H,O* OH, H2O (excess) 1. CH3CH2MgBr (excess) 2. H30 NaBH4 (excess) Br 1) Mg, ether 2) H30*
alon 4) Design a synthetic route that would form the following ketone using Acetoacetic Ester or Malonic Ester Synthesis. You can utilize any aldehyde, ketone, ester alkyl halide, acid, base, and any additional inorganic reagent or solvent needed. Remember to be specific with your choice of reagents and cond itions. Draw out each synthetic step with the reagent(s) needed for performing that step. (20 Pts) Sorry this ir all Over the plau... ( tricd to draN Prth но
4. Provide reasonable products or reactants for the reactions below. (a) (reaction of aldehyde/ketone) H' Η CHO HO (b) (esterification) you 3) HCI 1) NaOH 2) HCI (d) (reaction of aldehyde/ketone) Tollen's reagent (e) (reaction of aldehyde/ketone) но он H* (1) (reduction reaction) NaBH ELOH
6. Give reactants, reagents, and/or products for the following reactions, as appropriate. SOCI2 он 1) NaBH, (excess) OCH3 2) H307 OH, H20 (excess) 1. CH3CH2MgBr (excess) 2. H30*
8. Give products or required starting materials for these crossed-Claisen condensations that use two different esters. Note that the first ester is added to the base to form an enolate. (If the base were added to the ester, enolates would form and react with the ester present in the flask). Give the enolate for the first reaction. 1) O 2) OK iPro ОMe Meo t-butoxide THF 1) 2) N LÝ OMe Eto Meo LDA 1) 2) Meo Оме Eto LDA...
Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give cis-4-Isopropylcyclohexanol. Alkyl halide reactant: OH Edit CH3 Nucleophile reactant: CH Edit cis-4-Isopropylcyclohexanol product: он Edit CH3
Give the reactants that are required to form the following andol condensation product. CHO
Problem 6.26f Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give the following compound: Problem 6.26f Draw an appropriate alkyl halide and a nucleophile in conjugate base form that are required to give the following compound: Alkyl halide reactant: 2 Edit Nucleophile reactant: Edit
The Robinson annulation involves two sequential reactions, a Michael addition and an aldol condensation, resulting in the formation of a cyclohexenone derivative.Draw the structure of the two neutral reactants required to form the product shown below.