The mechanism of the conversion of alpha ketoglutarate to succinyl CoA catalyzed by alpha ketoglutarate dehydrogenase complex involves the following steps:
Outline the mechanism of the conversion of alpha ketoglutarate to succinyl Co wedge catalyzed by alpha...
Please draw the complete mechanism for the conversion of isocitrate to alpha-ketoglutarate. Be sure to include any intermediate structures and be clear where your arrows are coming from and going to.
(5 points): The alpha-ketogluterate dehydrogenase complex uses three proteins and 5 different co-factors to convert pyruvate to acetyl-CoA. Identify these three proteins and five co-factors and describe the chemical role that each plays in the reaction mechanism of the a-KGDH complex. Write the balanced equation for the overall reaction catalyzed by this enzyme.
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....