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20 marks
Discussion Dry column chromatography. State 2 advantages and 1 disadvantage over conventional column chromatogr.
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➢Advantages of Column chromatography
1.It can be used in both analytical and preparative applications.
2.It is used to determine the number of components of a mixture.
3.It is also used to separate and purify substantial quantities of those components for subsequentanalysis.
➢Disadvantages of Column Chromatography
1.Properly setting up the column requires some technical skill and manual dexterity.
2.It is very time consuming and tedious, especially for large samples.
3.Collecting vessels must be frequently switched and solvent levels need to be topped up.

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