Can all abnormal hemoglobins be diagnosed by electrophoresis? Explain
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Can all abnormal hemoglobins be diagnosed by electrophoresis? Explain
Explain how multicollinearity can be diagnosed?
Gel electrophoresis. Polypeptides can be separated by electrophoresis according to their relative content of acidic and basic residues. The isoelectric point (pI) of a polypeptide is the pH at which its net charge is zero. (See Fig 3.11 of your textbook). A) At physiological pH (= 7.4), what is the net charge on the tripeptide Asp-Arg-Glu-His? B) Calculate the pI of this tetrapeptide. [Hint: Using the pK, values in Table 2.1 and the Henderson-Hasselbalch equation, determine the pH when the...
2. Explain why electroosmotic flow predominates capillary electrophoresis and how it can affect the migration (elution) of positive, negative, and neutral species within a sample.
Gel electrophoresis can be used to separate molecules by select all that apply a.length. b.size. c.charge. d.weight. e.# of atoms.
Question 12 Which of the following is NOT a characteristic of hemoglobinopathies? All are manifested in clinically significant conditions Abnormal hemoglobins are synthesized Result in a defect in structural integrity of function of the hemoglobin molecule Result from abnormalities or genetic mutations
Explain the results of the following cross in Drosophila: abnormal wing x abnormal wing The progeny: 53 - normal wing; 97 - abnormal wing. Explain the mode of inheritance and ratios of the progeny (use the chi-square test, if necessary). Write down the scheme of the cross and genotypes of the parents and offspring.
Differentiate between two normal and two abnormal findings on a neurologic exam. Explain what the abnormal findings may indicate and the patient education that would be required when explaining the abnormal findings.
IN YOUROWN WORDS, briefly explain how gel electrophoresis works.
Explain the process called electrophoresis to distinguish hidden genetic variation in the form of isozymes.
Explain ejection fraction and list normal and abnormal values.