When will a carbon atom act as a nucleophile; when as an electrophile?
When will a carbon atom act as a nucleophile; when as an electrophile?
Homework Answers
Carbon oxidation state varied from +4 to -4 state
when carbon is bounded to an electronegative atom such as halogens, nitrogen or oxygen, the shared pair of electrons are shifted more towards the electronegative atom. Thus carbon in such cases have a +ve charge on it and acts as a electrophile for example in alkyl halides.
when the leaving group attached to carbon leaves with a +ve charge, such that leaving behind its shared pair of electron. The carbon gets a -ve charge and in such cases it acts as a nucleophile for example in grignard reagents.
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When will a carbon atom act as a nucleophile; when as an
electrophile?
Which collision angles between the nucleophile and electrophile can result in a new Nucleophile-carbon bond? indicates...
Which collision angles between the nucleophile and electrophile can result in a new Nucleophile-carbon bond? indicates Nucleophile's collision ange CG
sn2, Nucleophile and eclectrophile 9. Consider the SN2 product below. Provide a nucleophile and electrophile the...
sn2, Nucleophile and eclectrophile
9. Consider the SN2 product below. Provide a nucleophile and electrophile the below. Provide a nucleophile and electrophile that, when reacted, would result in the product provided. Multiple correct options exist. (2 points) DY= electrophile nucleophile
4. (6pts) Label each molecule as a nucleophile or electrophile AND draw an arrow pointing to...
4. (6pts) Label each molecule as a nucleophile or electrophile AND draw an arrow pointing to the atom on the molecule that would be the nucleophile or electrophile CI CEN HTΉ I verbo on si smith H-C-OH I-O-I H₃C – NH₂ Hool H3CH
In the introduction, hydroxide ion acts as a nucleophile by attacking a carbon atom in 2-...
In the introduction, hydroxide ion acts as a nucleophile by attacking a carbon atom in 2- bromooctane (Eq. 1). Why is that specific carbon atom a good target? Why doesn’t the hydroxide attack any of the other carbon atoms in 2-bromooctane? Why can the carbon atom that is attacked be considered “electron-poor”?
Which is the nucleophile and which is the electrophile of this Biginelli reaction? Your Biginelli reaction...
Which is the nucleophile and
which is the electrophile of this Biginelli reaction?
Your Biginelli reaction is performed under Lewis-acidic conditions. One possible step in the synthesis, as shown in the lab manual, is the Knovenagel condensation between benzaldehyde and ethyl acetoactate: Ob el con OEt 0OET Consider the mechanism of the Knovenagel reaction, and the reaction conditions. Then, from the list of species shown below, choose the electrophile and the nucleophile that would be involved in the carbon-carbon bond-forming...
Why does the C carbon the one atom that reacts more like a nucleophile instead of...
Why does the C carbon the one atom that reacts more like a
nucleophile instead of the O- ? (This is an Aldol reaction)
β.bydeKJcerbear1;s thinsmedate peded of an 4LLI reachan if the male. on ishealed, then dehydntbn。ccurs , has reimance Hー あ Hl why does thi, O, react,咻but the C-dees? why cles the C act more like a ele phile
For the following reaction, label the nucleophile, electrophile, and leaving group, Br + + Br Nucleophile...
For the following reaction, label the nucleophile, electrophile, and leaving group, Br + + Br Nucleophile Select] Electrophile (Select] Leaving Group [Select] For each of the following pairs, indicate with molecule is the better (stronger) nucleophile. [Select] [ Select] Z-I [Select) [Select]
Hydroxide ion acts as a nucleophile by attacking a carbon atom in 2-bromooctane. 1. Why is that specific carbon ato...
Hydroxide ion acts as a nucleophile by attacking a carbon atom
in 2-bromooctane.
1. Why is that specific carbon atom a good target?
2. Why doesn't the OH attack any other carbons in
2-bromooctane?
3. Why can the carbon atom that is attacked be considered
"electron poor"?
SN2 + : ОН + : Br Eq. 1 A Br ОН
Classify each of the following as an electrophile or a nucleophile.
Classify each of the following as an electrophile or a nucleophile.
Choose the best option for the nucleophile precursor to the B-ketoester intermediate. CO2CH2CH3 electrophile nucleophile
Choose the best option for the nucleophile precursor to the B-ketoester intermediate. CO2CH2CH3 electrophile nucleophile
Which collision angles between the nucleophile and electrophile can result in a new Nucleophile-carbon bond? indicates Nucleophile's collision ange CG
sn2, Nucleophile and eclectrophile
9. Consider the SN2 product below. Provide a nucleophile and electrophile the below. Provide a nucleophile and electrophile that, when reacted, would result in the product provided. Multiple correct options exist. (2 points) DY= electrophile nucleophile
4. (6pts) Label each molecule as a nucleophile or electrophile AND draw an arrow pointing to the atom on the molecule that would be the nucleophile or electrophile CI CEN HTΉ I verbo on si smith H-C-OH I-O-I H₃C – NH₂ Hool H3CH
Which is the nucleophile and
which is the electrophile of this Biginelli reaction?
Your Biginelli reaction is performed under Lewis-acidic conditions. One possible step in the synthesis, as shown in the lab manual, is the Knovenagel condensation between benzaldehyde and ethyl acetoactate: Ob el con OEt 0OET Consider the mechanism of the Knovenagel reaction, and the reaction conditions. Then, from the list of species shown below, choose the electrophile and the nucleophile that would be involved in the carbon-carbon bond-forming...
Why does the C carbon the one atom that reacts more like a
nucleophile instead of the O- ? (This is an Aldol reaction)
β.bydeKJcerbear1;s thinsmedate peded of an 4LLI reachan if the male. on ishealed, then dehydntbn。ccurs , has reimance Hー あ Hl why does thi, O, react,咻but the C-dees? why cles the C act more like a ele phile
For the following reaction, label the nucleophile, electrophile, and leaving group, Br + + Br Nucleophile Select] Electrophile (Select] Leaving Group [Select] For each of the following pairs, indicate with molecule is the better (stronger) nucleophile. [Select] [ Select] Z-I [Select) [Select]
Hydroxide ion acts as a nucleophile by attacking a carbon atom
in 2-bromooctane.
1. Why is that specific carbon atom a good target?
2. Why doesn't the OH attack any other carbons in
2-bromooctane?
3. Why can the carbon atom that is attacked be considered
"electron poor"?
SN2 + : ОН + : Br Eq. 1 A Br ОН
Classify each of the following as an electrophile or a nucleophile.
Choose the best option for the nucleophile precursor to the B-ketoester intermediate. CO2CH2CH3 electrophile nucleophile
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