How general or accurate is Zaitsev
answers
The rule that states that if more than one alkene can beformed by an elimination reaction, the more stable alkene is themajor product. In general, the compound that has a more highlysubstituted C=C double bond is more stable due to the electrondonating properties of the alkyl group. The rule is very generaland has many correct examples.
Post-Lab Questions 1. Give the expected Zaitsev and anti-Zaitsev products in the following reactions. Label the Zaitsev products. OH H2SO4 OH H2SO4
Draw the Zaitsev product formed when 2,3-dimethylpentan-3-ol
undergoes an E1 dehydration.
Draw the Zaitsev product formed when 2,3-dimethylpentan-3-ol undergoes an E1 dehydration.
Draw the Zaitsev product formed when 2,3-dimethylpentan-3-ol
undergoes an E1 dehydration.
Draw the Zaitsev product formed when 2,3-dimethylpentan-3-ol undergoes an E1 dehydration.
1. Draw the possible E2 products and circle the Zaitsev
products.
2. Draw a Newman projection for the preferred anti-periplanar
conformation leading to the Zaitsev product.
3. Predict the stereochemistry of the Zaitsev products based on
your Newman projection.
Hi! Can someone help me go through the correct steps? Ignore the
pen marks I made:)
eoh E2 Br 2 1. Draw the possible E2 products and circle the Zaitsev products 2. Draw a Newman projection for the preferred anti-periplanar conformation...
how many synthetic connections for alkene and
alkyne
2. Is the Zaitsev Rule wrong? Explain the following observation. Make comparative predictions about the rate constants ki and k2. 80% 20% on CH₂ 100% 3. Using curved arrows to show the movement of electron pairs, give a detailed mechanism for the following reactions. H2SO4 H20 195010 - + H20 H2SO4 H2O CH3 H3C-C-CH2-OH- CHE HECH = + H₂O H₃C CH₂ 4. See how many synthetic connections you can make on the...
Draw the structure of only the Zaitsev product that would be obtained from the dehydration of 1-methylcyclohexanol.
For the following dehydrohalogenation (E2) reaction, draw the
Zaitsev product(s), showing the stereochemistry clearly. If there
is more than one organic product, both products can be drawn in the
same box.the hint:Consider that the reaction is an elimination in the presence of
a relatively small base to give the Zaitsev product, which is the
most stable. Also consider the stereochemistry of the reactant and
that the elimination must be anti-periplanar.
the Complete the following reaction sequence. Choose only one of the Zaitsev products (D or E) to complete ozonalys step. A; B; C and F, 2 pts each. D and E, 1 pt each. 4-methylpentan-2-one PCC H2SO4, heat он i) 03,-78°C 2) (CH3)2S +Zaitsev products only 3,5-dimethylhexan-3-ol
For each reaction: draw all products, label the Zaitsev and
Hofmann products, if there is more than one elimination product,
and circle the major product.
Hint: LDA is a strong bulky base
4. (16 pts) For each reaction: draw all products (use your Substitution/Elimination Review PowerPoint and your book!) label the Zaitsev and Hofmann products, if there is more than one elimination product. circle the major product. Hint: LDA is a strong bulky base E1OH OTs CI LDA NaOH Br...
complete the following reaction sequence. choose only one of the
Zaitsev products (D or E) to complete the ozonalys step.
Date Quiz 6 (10 pts) Complete the following reaction sequence. Choose only one of the Za only one of the Zaitsev products (DoE) to complete the ozonalys step. A; B; C and F, 2 pts each. D and E, 1 pt ench. PCC 4-methylpentan-2-one H SO4, heat 1) 03. -78°C 2) (CH3), + Zaitsey products only 3,5-dimethylhexan-3-ol