Question

draw the major products (a - d), suitable reactants (e – i), or list the reagents required (j – o) for the reactions shown below. Identify the stereochemistry for reactions where stereoselectivity is observed. Indicate, using a numbered list of reagents, when multiple sequential reactions are required to generate the desired product. Don’t worry about solvents but you should indicate the specific acids and/or bases required for the desired reaction

O 0 Eto I CH3 он * BrsCH NH3+ COOH COO-

Answer 1

gwen reactions Mile acidic i 12& nbuli CHI Here we should use two Equivalents of n-Bubi to film dianion. After react with Chi do film final product so option is 24 N-Buwi Boc N 1 In acid medier heat lat In Acidic medin Boc [PH 24 Deprotected up Estos hydrolysis ti i on to a In basic medium a Endlate films Enolate Jon a reacts with alkyl halides To 6.ro Be in spr manner. Soko on heat eto I Ester hydrolysis followed by de carboxylation I-Co2 & OH pour end tudo phu Enol keto Ph

OKO +oܬܐ ܐ - ܙ8 + + ► undergo Aldol reaction in si basie Aldehyds up Ketones medium OH Bm Nooth BOBCH -Cgtu QUB ? # ܢ 38* coon + Chori Bromofolm Reaction in presence Meruy Ketones undergo | ܘܨܙ0| .& !o