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Est. Length: 2:00:00 Haylie Simmons: Attempt 1 femtograms (fg) DNA per cell 0 5 10 15 20 25 Time (hours) 30 35 40 45 If the r
0 5 10 15 30 35 40 45 20 25 Time (hours) If the researchers added Colchicine (an inhibitor of microtubule polymerization) at
0 0
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Answer: DNA content per cell would be at about 10 fg

At hour 25 the DNA content is 10 fg and at hour 35, it is 5 fg. This shows that in this interval, cell division is taking place. Colchicine is an anti-mitotic drug that suspends all cells in metaphase by inhibiting microtubule polymerization. If cells at 25 hours is treated with colchicine, cell division would proceed but then stop at metaphase. Without completion of cell division, DNA content cannot get halved, and hence would remain at 10 fg.

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