When running molecular simulations, what is the consequence of not capping the n- and c-terminus? I...
When running molecular simulations, what is the consequence of not capping the n- and c-terminus?
I have been following gromacs tutorials and haven't come across any that deal with capping the termini, so is it important?
Homework Answers
Interesting question. I have to admit, that I haven't really come across it, but for the moment it seems to me that this mechanism is used mainly to protect short alpha helices and stabilize them. See this articles: "Helix stop signals in proteins and peptides: the capping box." and this one: "Helix capping." A lot of research is done in combination with actin filaments, where the capping plays an important role in stabilizing the filament strands - either prohibiting the addition of new monomers and on the other hand preventing the removal of elements from the polymer strand. This review gives an overview:"F-actin capping proteins." This research article might also be interesting when doing simulations:"N- and C-capping preferences for all 20 amino acids in alpha-helical peptides." As always, if you have some problems with access to the articles, let me know.
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When running molecular simulations, what is the consequence of
not capping the n- and c-terminus?
I...
When amino acid monomers are joined together, they are always arranged so that the 'C-terminus' of...
When amino acid monomers are joined together, they are always arranged so that the 'C-terminus' of one amino acid is covalently bonded to the 'N-terminus' of the other. How would this 'polymerization' occur chemically? Draw your answer on a paper using the figure below and indicate what this chemical process is called: Upload the picture of the file. R. 20 H N co - I 0 ні H I I
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IMPORTANT: I don't need help with "a". However, I do need help
with b&c
IMPORTANT: I understand that there's a walkthrough given bellow.
However, I do not understand the walkthrough given for b&c.
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- Why does E(x)+E(y)=2u (2 mew)?
-What is this?: I honestly have no idea what it
is. Please explain to me what it is and what its significance is
within the problem.
-This may be the same thing as the symbol above, but just in...
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