Question

We learned that to create vicinal diols from alkenes, the cis-1,2-diol or trans-1,2 diol required very different reagents. This isn't always the case and one notable reaction that defies this convention is the Prévost reaction! (4 points) To make the cis-diol, we typically use osmium tetroxide (catalytic amounts!). What other reagent combination would work for this particular transformation? a. OH OH (rac b. (4 points) To make the trans-diol, what reagent combination would be employed? ?? 1F2 OH (4 points) The Prévost reaction is actually capable of forming either of the vicinal diols depending on whether or not water is present. The reaction conditions are shown below c. R (1 equiv) )% RCO-Ag (2 equiv) ?? R14 base inert solvent ac) ?? 4 Based on the presence of elemental iodine in the reaction mixture, what do you think the critical first intermediate should be for the reaction?

Answer 1