Question

TARGET CELLS ACTION DISEASE HORMONE WORKSHEET HYPO ANTERIOR PITUITARY CRH ACTH TRH TSH GnRH FSH GnRH LH PRH Prolactin GHRH GH POSTERIOR PITUITARY ADH (Anti-diuretic hormone) Oxytocin THYROID GLAND T3 Thyroxine (T4) Calcitonin ADRENAL GLAND CORTEX Cortisol (glucocorticoid) Aldosterone (mineralocorticoid) MEDULLA Epinephrine / NE PARATHYROID GLAND PTH (Parathyroid hormone) HEART ANP (Atrial natiuretic peptide) KIDNEYS Renin --> angiotensin --> aldosterone Erythropoietin PANCREAS B-islet cells Insulin a-islet cells Glucagon

Answer 1

please find answer in table below.

	Anterior pituitary	Target cells	Action	Disease
CRH	ACTH	Adrenal cortex	Regulate level of cortisol	Cushing syndrome
TRH	TSH	Thyroid gland	Stimulate secretion of thyroid hormone	Central hypothyroidism
GnRH	FSH	Certoli cells in testes and granulosa cells of overy	Stimulate maturation of germ cells	Primary ovarian insufficiency
GnRH	LH	In testes receptor on leydig cells. In ovary theca cell	Production of testosterone in males ,in females of testosterone which convert in oestrogen	Infertility , polycystic ovary syndrome
PRH	Prolactin	Mammary glands ,ovaries ,pituitary gland	Promote milk production from mammary glands	Hyper prolactnemia
GHRH	GH	Liver and adipose tissue	Promote growth of body	Gigantism, dwarfism
	POSTERIOR PITUITARY
	ADH	Tubular cells of kidney	Water reabsorption in kidney	Diabetes ,insipidus
	oxytocin	Uterus ,mammary glands	Promote contraction of uterus during labour and stimulate milk secretion for breast feeding after child birth	Lack of oxytocin prevent breast feeding
	THYROID GLAND
	T3	Brain ,bone ,heart , muscles	Regulate body temperature ,heart rate, metabolism	Hypothyroidism and hyperthyroidism
	Thyroxin(T4 )	Brain ,bone ,heart, muscles	Regulate body temperature ,heart rate, metabolism, mood , body weight	Hypothyroidism and hyperthyroidism
	calcitonin	Bone	Regulate calcium level	Medullary thyroid cancer
	ADRENAL GLAND
	CORTEX
	Cortisol	Most cells in the body	Helps in metabolism of fat, carbohydrate and protein, increase blood sugar level.	Hypercortisolism
	aldosterone	kidney	Electrolyte and fluid balance	Conn’s syndrome
	MEDULLA
	Epinephrine/NE	Most cells in the body	Increase heart rate ,elevate BP , vasoconstriction , glucose metabolism	Addison’s
	PARATHYROID GLAND
	PTH	Bone and kidney	Regulation of calcium homeostasis	Hyperparathyroidism
	HEART
	ANP	Adrenal gland	Maintaining fluid and blood pressure	Hypertension ,heart failure
	KIDNEYS
	renin	Angiotensinogen of liver	Regulate blood pressure ,fluid and electrolyte balance	hypertension
	Erythropoietin	Bone marrow	Control RBC production	polycythaemia
	PANCREAS
	B- Islet cells
	insulin	Liver ,muscle ,adipose tissue	Regulation of blood sugar level	Diabetes
	Islet cells
	Glucagon	liver	Regulation of blood sugar level	glucagon