Question

In this assignment the role of macrophages in the metastatic mechanisms of AGS gastric cancer cells are explored. AGS cells are normally non-invasive. To investigate mechanisms that could cause these cells to become invasive, "matrigel invasion chambers" were used, as shown below. Cancer cells Macrophages Matrigel Mac Click here to download image Double decker chambers are used where cells are grown in separate upper and lower compartments that are separated by "matrigel". Matrigel is a gel that is mostly made of laminin and collagen. Laminin is similar in function to fibronectin.

Answer 1

Answer

Option C is correct i.e " Macrophage secreted soluble molecules".

Explanation

As macrophages must be secreting some molecules that make AGS cells invasive like some cytokines (TGF- $\beta$ ) secreted by macrophages.