A 20-year old gardener presents to his family physician for treatment of what he described as poison ivy The patient hand and arm appear red and are covered with oozing blisters and crusts. Which of the following best describes the pathogenesis of this skin lesions?
Cytotoxic antibody production
Delayed-type hypersensitivity
Deposition of antigluten antibodies
Deposition of circulating immune complexes
Ig-medicated mast cell degranulation
its IgE mediated mast cell degranulation..because he is a gardener..and when allergins are common and when they enter the body,IgE activated and bind to mast cells releasing histamine and prostaglandins causing vasodilation and allergic response..its also called Type 1 hypersensitivity or immediate type of hypersensitivity reaction
Delayed-type hypersensitivity
Contact with poison ivy does not show immediate reaction, rather, the immune response is visible several hours after exposure to the antigen. The response is mediated by TDTH cells. Monocytes/macrophates migrate to the site of antigen exposure and initiate inflammatory response which end in localized reactions.
A 20-year old gardener presents to his family physician for treatment of what he described as...