Problem 5: Draw the reaction products for the two schemes shown below. 0 (1) N cat.H*...
4. Draw the products of the following sequences of reactions. 1) NaOET, HOE 1) NaOEt Eto OEt 2) H3O+ 2) Br | 1) LDA, -78°C 2) 0 H30+ heat H 3) NaOH, heat 1) LDA (1.1 equiv), -78°C, THE 2) CH3Br 1) CH3CH2MgBr 2) H30* H2, Pd-C LU H2SO4 NaOH, H2O 1) LDA, -78°C 2) HOE 3) H30+ 1) O3 2) CH2SCH3
Predict the products for each reaction shown below N NaOH N NaOH THF LDA 1) NaH, THF EtO THF-78 °C 2) CH3CH2Br heat HO CH3COOH KOH CH3NH2 KOH MeOH 1) NaOMe, MeOH 1) HCI, H20 OH 2) PhCH2Br 2) 180 °C
2. Draw the major organic product for each of the following reaction schemes. (1 pt each) a) POCl3, pyridine HO or H3O, heat b) H3O heat c) 0 1. LDA OEt 2 3. Show the structure of each intermediate and product for the following synthetic scheme. Your answer does not need to show the electron flow with arrows but should have correct formal charges. (2 pts) Co Et 1. NaOEt, EtOH Co2Et 2. H30", heat
1) Reactions. Provide the major product for each reaction sequence, account for stereochemistry 1) PCC, CHCI 2) Bry, acetic acid 3) KOBU, A 4) NaOEI, ETOH, P CO- 5) H30 workup 6) THF, H.COPPA HC CH2 O e .cat. Pd(OAc) cat. PPh. DMF, EIN 2) LDA, THF. -78 °C 3) Chichen H3O* workup 4) NaBH, EtOH, then H3O+ workup 5) cat. TSOH, benzaldehyde (c) L AL SUO TESTE TO 1) cat. H2SO4. A лон 2) O3, CH, Cl, then (CH),...
2. Draw two possible products for the reaction shown below. Are your products formed as a racemic mixture? Which of your two products do you expect to be the major one? Why? 1 equiv. Br2 THF possible product 1 possible product 2 Possible product 1 a racemic mixture? Yes No Possible product 2 a racemic mixture? Yes No Which would be major? Why?
1. Provide the major products for the following reactions. (5) CH3ONa CH3! 1. LDA. -78 deg 2. (CH3)2 Sici @ 2% NaOH CH3OH, heat @ C=0 HCI coEt NaOEVETOH H30*heat Br Br CO,Et
1) Draw the major product of the following intramolecular reaction. 2) Draw the major product of the following reaction that begins with a retro-aldol, followed by an intramolecular aldol condensation. 3) Determine and draw the structures of compounds A and B only. Do not draw the structure of compound X. Place each structure above its letter. HINT: Both A and B are esters. 4) Draw a curved arrow mechanism for the following acid-catalyzed isomerization reaction. You must show all intermediates....
1- Draw all of the expexted products from the reaction and explain. Draw the products of the reaction. (2 equiv.) NH Select Draw / H2C--0-0- HC=CH CH + OH- - CH3 HC-CH cs H3C-CH2-C-N-CH3 + HCI heat
1. Draw the primary organic products in the boxes provided below. ~Br n-Buli (1) CH3CH2MgBr dry ether (2) Lindler catalyst H₂ (2) H30+ (3) H30+ Draw an electron pushing mechanism for the reaction shown below. (1) CH2CH2MgBr dry ether (2) (3) H30+
Propose an efficient synthesis for the transformation below, using two sequential reductive aminations. Enter the appropriate number or letter from the reagent list handout. Propose an efficient synthesis for the transformation below, using two sequential reductive aminations. Enter the appropriate number or letter from the reagent list handout. Step 1 + NaBH3CN, H+, Step 2 - NaBH3CN, H+ Reagent List (Updated 4/30/2020) Enter # or letter in the appropriate boxes. Note: Exam responses are case insensitive Alkyl Halides (X = Cl,...