Question

1 points SA Liver cells and smooth muscle cells both possess the BP-adrenergic receptor. Activation of this receptor by circulating adrenaline leads to glycogen breakdown in a liver cell and relaxation in a smooth muscle cell. These different outcomes following interaction with the same initial stimulus can be traced to different intracellular proteins that become engaged in the response in these two types of cells. True False

Answer 1

True. Liver cells and smooth muscle cells both possess beta-adrenergic receptors which are activated on binding of adrenalin (epinephrine) and cause two different responses in liver and smooth muscle cells, glycogenolysis (breakdown of glycogen) and relaxation respectively. In both type of cells binding of epinephrine to the beta-adrenergic receptor triggers cAMP dependent signalling mechanism triggering glycogenolysis and relaxation.