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Does the linked action of the Na-H antiporter and Na-K pump cause imbalances in either the...

Does the linked action of the Na-H antiporter and Na-K pump cause

imbalances in either the K+ concentration or the mem-
brane potential? Why or why not? Please draw a diagram as well.

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Answer #1

Ion transporters are "linked" together - not physically, but as a consequence of their actions. For example, cells can raise their intracellular pH, when it becomes too acidic, by exchanging external Na for internal H using a Na-H antiporter. The change in internal Na is then redressed using the Na-K pump.

The linked action of these 2 pumps moves 3H out for every 2K that are brought into the cell, thereby increasing both the internal K concentration and the membrane potential .

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