Question

Which of the following guidelines is not necessary in determining whether or not an association is...

Which of the following guidelines is not necessary in determining whether or not an association is causal?

a) Biologic plausibility

b) Randomization

c) Temporal relationship

d) Consistency with other findings

e) Dose-response effect

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Answer #1

Randomization is the answer to this question.

To determine the causal association in the epidemiologic study scientist Bradford hill designed a guideline which includes nine criteria (Strength (effect size), Consistency (reproducibility), Specificity, Temporality, Biological gradient, Plausibility, Coherence, Experiment, Analogy).

Out of all nine, randomization is the odd one out. See the second criteria which are deals with the consistency so there is no scope for any randomization.

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