Bioinformatics Assemble the error-free reads from a circular genome on the following dataset. You do not...
Bioinformatics
Assemble the error-free reads from a circular genome on the following dataset. You do not need to consider the reverse complement of the reads.
- As the reads do not have the same length, convert the reads to 4-mers using the method proposed by Idury and Waterman.
- Build the de Bruijn graph B3 for the set of 4-mers.
- Find the genome using the graph.
Dataset:
CGTTCT CTAG GACGT TAGAC TCTA
Homework Answers
according to data set given ;-
CGTTCT CTAG GACGT TAGAC TCTA
ANSWER ;- GCAAGA GATC CTGCA ATCTG AGAT
NOTE ;-ADENINE AND THYMINE WILL BE PAIRED WITH TWO COVALENT BONDS
GUANINE AND CYTOSINE WILL BE PAIRED WITH THREE COVALENT BONDS
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