Why is a Knoevenagel reaction chosen in one case and Pechmann in the other? How do the functional groups of the starting materials influence the choice of reaction conditions?
In pechmann condensation, pbenol and it's derivative's are used and coumarin derivative's are the product.
While knovengal condensation uses carbonyl compounds and products are conjugated ester.
And beta keto esters or diesters are the another set of reagents in both reactions.
Why is a Knoevenagel reaction chosen in one case and Pechmann in the other? How do...
explain why one is chosen over the other.
Problem 4 Propose reaction conditions that will give the indicated product. о ОН ОН ОН “ ОН ОН
1.
Why do we want a reaction to go to completion?
2. In general, what are the most reactive parts of a
molecule?
3. Which TLC plate shows a completed reaction?
SM = Starting Material, RXN = Reaction, P= Product
Why do we want a reaction to go to completion?! Consuming all the starting material means less waste Consuming all the starting material means you don't have to separate the starting material from your product o Consuming all the starting...
Discuss the polycondensation reaction. Why would water interfere with it? In case experiment failed-explanation is expected. Why it failed? What could be improved. Explain molecular structure vs signal relationship . In your discussion consider the following concepts: polycondensation, functional groups, fibril formation and stabilization (interchain molecular itneractions) , reaction yield and the role of NaOH solution used in the reaction Can you answer these questions based on the Synthesis of Nylon-6,6 using adipoyl chloride and 1,6-hexanediamine
Why do strategic trade policies normally attract trade retaliation actions from other countries? Examine a case study of your choice and analyse its implications.
.
Find one example of an anti-cancer or anti- viral drug (other types of drugs are also okay) that has at least one chiral center in its structure. Write a brief overview of how this drug used and why it is effective (cite source!). Draw its structure and mark all the stereocenters with a star. Assign each stereocenter as R or S (in case the drug is used as a racemic mixture you can show one of the stereoisomers as...
Why do you think that the functional groups of alcohols, thiols, and ethers are grouped together? Describe the types of intermolecular forces that you think affect the properties of alkanes and the other functional groups of organic compounds discussed in this chapter.
What is one reaction you predict could be used to make Ivabradine*? Give the product/starting material, the reagent(s), and the curly arrow reaction mechanism. (No simple acid-base reactions.) (Note that these are predicted reactions, based on the functional groups present, they do not have to be reactions of the drug actually does undergo.)
Draw the starting materials for stilbene synthesis (Wittig reaction): one aldehyde + one ylide compound Draw the arrow-pushing mechanism for the ylide formation. Draw the arrow-pushing mechanism for formation of stilbene. Please be specific in the compounds, in other words not with R' groups.
Draw the starting materials for stilbene synthesis (Wittig reaction): one aldehyde + one ylide compound Draw the arrow-pushing mechanism for the ylide formation. Draw the arrow-pushing mechanism for formation of benzil. Please be specific in the compounds, in other words not with R' groups. Thank you!
21. Do Only One! Propose a multistep synthesis using the starting materials shown and any other reagents/reactants you need. To maximize partial credit, be sure to draw out the products of each reaction you propose. You do not need to draw mechanisms for full credit. (7 points) o by OR ОMe