Question

Regarding the nucleotides metabolism: Chose correct Answers:

PRPP is an activated form of the ribose The salvage pathway of purines has a lower energy cost compared to the de novo synthesis pathway The aspartate transcarbamoylase is the control enzyme for the de novo synthesis pathway of purines The glutamine is essential for the de novo synthesis pf pyrimidines The synthesis of dTMP uses the dUMP as a substrate

Answer 1

Regarding the nucleotides metabolism the correct answers are:

• PRPP is an activated form of the ribose.(5- phosphoribosyl 1 pyrophosphate)
• Tha salvage pathway of purines has a lower energy cost compared to the de novo synthesis pathway.
• The glutamine is essential for the de nove synthesis os pyrmidine, since it acts as a factor for two enzymes in pyrimidine synthesis.  
• The synthesis of dTMP uses the d UMP as a substrate with the enzyme being Thymidylate synthetase.

The incorrect statement is that:

Aspartate carbamoylase is the control enzyme for de novo synthesis of purines, since it is the control enzyme for the de novo synthesis of pyrimidines.