What is the major new absoption in the IR of salicylic acid that confirms hydrolysis has occured?
Hydrolysis of aspirin gives salicylic acid
Salicylic acid shows a broad peak at 3350 cm-1 for the O-H stretch
this confirms that hydrolysis is complete.
What is the major new absoption in the IR of salicylic acid that confirms hydrolysis has occured?
1.Which protons in methyl salicylate are resonsible for the resonance at 10.7 ppm? Which are responsible forthe resonance at 3.9 ppm? 2. Which carbon in methyl salicylate is respocsible for the resonance at 170.6 ppm? Which is responsible for the resonance at 52.2 ppm? 3. In the aromatic area of the proton NMR of methyl salicylate there is a doublet at 7.81 ppm. Which aromatic proton in the structure is responsile for this resonance? 4. What is the major new...
in moist environments aspirin can undergo hydrolysis and forms two products, salicylic acid and acetic acid. What smell would you expect to notice from a bottle of aspirin that has undergone hydrolysis ?
Synthesis of Aspirin Lab Quesitons 1. what major change in the IR spectrum would be expected upon conversion of salicylic acid to acetyl salicylic acid? 2. what purpose did the sulfuric acid serve in this reaction? what would happen if you used phosphoric acid, H3PO4 instead? 3. pick a prescription drug that you or your friends use. describe how it was synthesized
4. The base hydrolysis reaction for the conjugate base of salicylic acid (C6H (OH)(COOH)) is A: CHA(OH)(COOH) + H2O <==> CHA(OH)(COO) + H20* B: CH(OH)(COOH) + H2O <==> C6H4(OH)(COO) + OH C: CHA(OH)(COO) + H2O <==> C6H4(OH)(COOH) + OH Ky for this reaction is Check two (2) boxes. 0 O A (blank 1) B (blank 1) C (blank 1) 11.03 (blank 2) 1.07x10^-3 (blank 2) 9.33x10^-12 (blank 2) 0 0
When aspirin is hydrolyzed, what are the products? a.) salicylic acid and ethanol b.) salicylic acid and ethanal c.) salicylic acid and ethanoic acid d.) ethanol and acetic acid
what is the complete net reaction of: 1. Salicylic acid in heat 2. Salicylic acid in Aluminum Chloride/ Chloroform 3. Ethanolic Salicylic acid in 2% ethanolic Silver nitrate solution and 5% Nitric acid
Provide the major product in the reaction of salicylic acid with sodium iodide and bleach. Which step in an electrophilic aromatic substitution reaction is typically rate determining, formation of the sigma complex or loss of H+ by the sigma complex to form the product? What is the major product in nitration of 4-bromobenzoic acid? Using resonance structures, please explain the reason for this preference.
Identify the absence or presence of two significant bands in the IR spectra of isoamyl alcohol and isoamyl acetate that indicate an esterification has occured.
When old aspirin breaks down salicylic acid is formed. What functional group does salicylic acid have that aspirin does not? -OH Opera Olaondo acid catalyst + some stuff -©—OH 0-C-CH3 + CH3—C—OH acetic acid OH aspirin Salicylic acid
In the mechanism for formation of acetylsalicylic acid via reaction of salicylic acid with acetic anhydride, phosphoric acid acts as a catalyst by O cleaving an acetyl group from acetic anhydride via protonation of the bridging oxygen O neutralizing the hydroxide ion side product protonating the carbonyl oxygen in the acetic anhydride protonating the phenolic oxygen of salicylic acid Question 10 (3 points) What would be the predicted major product from the thermodynamically controlled dehydration of the following material OH