Question

Question 22 Which of the following is a way that Cytotoxic T cells can kill host cells? by secreting antibodies which inactivate the host cell by secreting granzymes which stimulate apoptosis by secreting interferons which degrade the host cell DNA by secreting tumor necrosis factor which stimulates apoptosis by secreting lysozyme which causes the host cell to lyse

Answer 1

Answer - by secreting granzymes which stimulate apoptosis.

Explanation -

Cytotoxic T cells are effector cells developed from lymphoid stem cells. They help in the destruction of foreign pathogen or an infected host cell. They release cytotoxic enzymes which kill the target cells.

First the Cytotoxic T cells binds with the infected host cell and produce Perforin molecules. These Perforin makes holes in the cell membrane ofinfected host cells. Then granzymes produced by the Cytotoxic T cells enter into the host cells. through these holes. The granzymes cause apoptosis of the infected host cells. Apoptosis is the programmed cell death.