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Below is the analysis of a potential antiretroviral drug for HIV from an organic Letters article. Answer the questions related to this retrosynthetic analysis. d pt) following a. For the retrosynthetic disconnection of D to E, draw out the best pair of syathons. and then use b. For the retrosynthesis of A to B c, label the carbons of structure A with numbers the same numweft te label the corresponding carbons of structures B and C. NH2 2-fluoroadenine HO A HO EFdA. symmetry PGO- OH desymmetrization Ho PGO C Figure 2. Synthetic strategy for EFdA. Draw a retrosynthesis corresponding to the following synthesis. Indicate the organic synthons for each step as well as the actual organic reactants. Be sure to show each disconnection and use appropriate symbols as shown in class. (1.5 pt) 1) NaH 1) Mg, ether NBS OH 2) CH3Br 2) CH20 3) H30*
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он PGO In this reaction sodium amide is used as acetyl proton abstracting base. Which act as a nucleophile to attack on carbo

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