Question

Why most enzymes have an optimum pH of around 7 while pepsin will be optimum at ph 2? Give a detail explanation!

Answer 1

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A pH of 7 called neutried environmant is the ophmum pH for almost all the enzy me will Tesults in low phH Eshrem ely hgh achuidy. Optomel emyma achudy. the loss of elabality and nomal onking andihon 15 at pH woski =7 (neutoal) foo most of the enrymes proved and discovered. Tem pors a hrte, , lonsc othes factors that affecs the' enzyme whicb 9s ouperiment aly elorength all are achody. Chemical struchre of Pepsis "Pepsin is one of the immpootant Proteoly tic enzypme gasteic juice As, ipachve fom pepsingen is poodured. în thhe mucesal 'Seen in the versleboak of

slomach Its impostent applicotns axe : D: Ginbbody dgeshm ) Pepsin is us el for a veziehy of applicabns IS polypphde R-and e': Leucme ,Pheny lahnie, Toyphophn and, h + 420 polyp ephde- fringimante

The ophmal pH of pepsin is at 2 m the acudie 4 is under shod that at low pH (most lic aud goup qud qudič ) the corboxyic get prolen ated , will be The carboxylie gooup achve sik of pepsin ashould bind to a hydrogen ahm to become iks prolenated forno . And this helps to chamical reochon o breoks on he colely ze the chemical banda and thoeb, chemical eochon. apeed up a
While we intake food along with food we needed bacteria and other useless or harmful things also enter along with it. To kill these type of external harmful bodies our stomach always maintain a killing mechanism. At pH 2 the gastric juices are able to kill bacterias as it is acidic .The cells in the stomach line secretes HCl which made the juices to remain in an acidic ondition.

Pepsinogen (the inactive for ) secreted in the stomach when comes in contact with acidic environment becomes active pepsin. Pepsin is a type of protease enzyme.