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1. Below are the structures and electron flow for the conversion of Compound Y into Compound...
1. NaOEt CO2Et 2. H30+ 3. heat Br. Br CORET + H3C V CO2H H₂C +...
1. NaOEt CO2Et 2. H30+ 3. heat Br. Br CORET + H3C V CO2H H₂C + CO2 + E H3C CO2Et The malonic ester synthesis is a carbonyl alkylation reaction. It is used to prepare carboxylic acids from primary alkyl halides, lengthening the carbon In progress by two atoms. Thus, the product can be visualized as being a "substituted acetic acid." The reaction consists of three steps: generation of the enolate anion followed by SN 2 reaction with a primary...
Need Help. Will Rate If Complete. 1) NaoEt, EtOH Br 2) O 3) H30+ / A....
Need Help. Will Rate If Complete.
1) NaoEt, EtOH Br 2) O 3) H30+ / A. 1) NaoEt, EtOH (s) ar 2) Y Br 3) Hz0+ / A 1) NaOme/MeOH ~ Br OMe 3) Hz0+/A. 1) NaOEt, EtOH 2) V Br 3) NaOEt, EtOH COOEt 5) H30+/A Robinson Annulation NaoEt, EtOH/A come lui OMe 28- The following molecules can be formed by either: Michael Reaction; Enamine Acylation; Acetoacetic Ester Synthesis; Michael Addition; Malonic Ester Synthesis; Robinson Annulation; Aldol Condensation; Claisen...
Provide a feasible multi-step synthesis for the following compound. Each blank corresponds to a one letter...
Provide a feasible multi-step synthesis for the following compound. Each blank corresponds to a one letter answer. Assume you have enough of your reagent to do the reaction: if you need two equivalence you don't need to repeat the letter. Assume a mild acid aqueous workup at the very end of the reaction sequence. COMPOUND: Starting material and Reagent Bank: D G ce * Br NaOEt, EtOH OEt B E H Br H307, heat Eto OEt F - Br CO2...
1) The reaction below proceeds via a multistep mechanism involving several intermediate structures en route to...
1) The reaction below proceeds via a multistep mechanism involving several intermediate structures en route to the final product. Some possible structures for the intermediates and product have been provided below. Decide which intermediates are involved in the reaction, and what the final product is, and place them in the correct order (e.g. A +B+C where C would be the final product isolated). (4 points) 1) NaOET, Eto OEt 2) NHACI, H20 Possible intermediates/products: Eto OET Eto OET Eto OET...
Thank you！ 9. What would be the product of the following conversion? 1. NaOEt, EIOH OEt...
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9. What would be the product of the following conversion? 1. NaOEt, EIOH OEt 2. H,о- OEt ОН О OEt OEt OEt OE OEt e. d. 10. What is the product of the Dieckmann condensation of the following diester? 1.NaOCH, CH,Oн HgCOoc coOCHs 2. H,0* осн, COOCH COOCH b. d. both a) and b) e. a), b), and c) a. C. 11. Consider the synthesis below. What is compound X? COOEt COOH 1. КОВи 1. NAOH, H2O, heat...
1. (1 pt) 12) Name the compound shown below. 2. (1 pt) 31) The carbon-carbon triple...
1. (1 pt) 12) Name the compound shown below. 2. (1 pt) 31) The carbon-carbon triple bond of an alkyne is composed of A) three o bonds B) three n bonds C) two o bonds and one a bond Done o bond and two a bonds 3. (1 pt) 46) Provide the structure of the major organic product(s) in the reaction sequence below. CH3CH2C=CH 1. NaNH2 " 2. PhCH2Br
Multiple Choice Section (0.5 pt each) 4. What is the most acidic hydrogen in the following compound? 1. (Review) Wh...
Multiple Choice Section (0.5 pt each) 4. What is the most acidic hydrogen in the following compound? 1. (Review) What functional group would the following reaction produce? В CH,CH,OH (b) В (a) A Нс. н pyridine (c) C (d) D H D H-- (a) amide (b) ester A H (c) anhydride (d) ketone 5. (Review) Which of the following represents a pair of keto-enol tautomers? 2. What would be the product of the reaction sequence shown below? SOCI2 1. DIBAL...
1 Use the structures below to answer the following questions Br Z=0 Br vi 3 1...
1 Use the structures below to answer the following questions Br Z=0 Br vi 3 1 2 a Enter the number of the compound that could undergo Nucleophilic Aromatic Substitution here b Enter the number of one of the compounds that will not undergo Nucleophilic Aromatic Substitution here c Explain why it will not undergo this reaction in the space below d Enter the number of one of the compounds that will not undergo Nucleophilic Aromatic Substitution here e Explain...
1) Consider the free radical monochlorination of 3-methylpentane and answer the following: a) How...
1) Consider the free radical monochlorination of 3-methylpentane and answer the following: a) How many products (including stereoisomers) are formed? _______ b) How many are chiral? ________ c) Would the major product of free radical bromination possess a chiral carbon? Yes or No 2) Which of the following functional groups can be generated in one step via SN2 or SN1 reaction? (Enter all that apply) a) Aldehyde b) Alcohol c) Alkene d) Alkyne e) Amine f) Carboxylic Acid g) Ester...
1) Consider the free radical monochlorination of 3-methylpentane and answer the following: a) How many products...
1) Consider the free radical monochlorination of 3-methylpentane and answer the following: a) How many products (including stereoisomers) are formed? _______ b) How many are chiral? ________ c) Would the major product of free radical bromination possess a chiral carbon? Yes or No 2) Which of the following functional groups can be generated in one step via SN2 or SN1 reaction? (Enter all that apply) a) Aldehyde b) Alcohol c) Alkene d) Alkyne e) Amine f) Carboxylic Acid g) Ester...
1. NaOEt CO2Et 2. H30+ 3. heat Br. Br CORET + H3C V CO2H H₂C + CO2 + E H3C CO2Et The malonic ester synthesis is a carbonyl alkylation reaction. It is used to prepare carboxylic acids from primary alkyl halides, lengthening the carbon In progress by two atoms. Thus, the product can be visualized as being a "substituted acetic acid." The reaction consists of three steps: generation of the enolate anion followed by SN 2 reaction with a primary...
Need Help. Will Rate If Complete.
1) NaoEt, EtOH Br 2) O 3) H30+ / A. 1) NaoEt, EtOH (s) ar 2) Y Br 3) Hz0+ / A 1) NaOme/MeOH ~ Br OMe 3) Hz0+/A. 1) NaOEt, EtOH 2) V Br 3) NaOEt, EtOH COOEt 5) H30+/A Robinson Annulation NaoEt, EtOH/A come lui OMe 28- The following molecules can be formed by either: Michael Reaction; Enamine Acylation; Acetoacetic Ester Synthesis; Michael Addition; Malonic Ester Synthesis; Robinson Annulation; Aldol Condensation; Claisen...
Provide a feasible multi-step synthesis for the following compound. Each blank corresponds to a one letter answer. Assume you have enough of your reagent to do the reaction: if you need two equivalence you don't need to repeat the letter. Assume a mild acid aqueous workup at the very end of the reaction sequence. COMPOUND: Starting material and Reagent Bank: D G ce * Br NaOEt, EtOH OEt B E H Br H307, heat Eto OEt F - Br CO2...
1) The reaction below proceeds via a multistep mechanism involving several intermediate structures en route to the final product. Some possible structures for the intermediates and product have been provided below. Decide which intermediates are involved in the reaction, and what the final product is, and place them in the correct order (e.g. A +B+C where C would be the final product isolated). (4 points) 1) NaOET, Eto OEt 2) NHACI, H20 Possible intermediates/products: Eto OET Eto OET Eto OET...
Thank you！
9. What would be the product of the following conversion? 1. NaOEt, EIOH OEt 2. H,о- OEt ОН О OEt OEt OEt OE OEt e. d. 10. What is the product of the Dieckmann condensation of the following diester? 1.NaOCH, CH,Oн HgCOoc coOCHs 2. H,0* осн, COOCH COOCH b. d. both a) and b) e. a), b), and c) a. C. 11. Consider the synthesis below. What is compound X? COOEt COOH 1. КОВи 1. NAOH, H2O, heat...
1. (1 pt) 12) Name the compound shown below. 2. (1 pt) 31) The carbon-carbon triple bond of an alkyne is composed of A) three o bonds B) three n bonds C) two o bonds and one a bond Done o bond and two a bonds 3. (1 pt) 46) Provide the structure of the major organic product(s) in the reaction sequence below. CH3CH2C=CH 1. NaNH2 " 2. PhCH2Br
Multiple Choice Section (0.5 pt each) 4. What is the most acidic hydrogen in the following compound? 1. (Review) What functional group would the following reaction produce? В CH,CH,OH (b) В (a) A Нс. н pyridine (c) C (d) D H D H-- (a) amide (b) ester A H (c) anhydride (d) ketone 5. (Review) Which of the following represents a pair of keto-enol tautomers? 2. What would be the product of the reaction sequence shown below? SOCI2 1. DIBAL...
1 Use the structures below to answer the following questions Br Z=0 Br vi 3 1 2 a Enter the number of the compound that could undergo Nucleophilic Aromatic Substitution here b Enter the number of one of the compounds that will not undergo Nucleophilic Aromatic Substitution here c Explain why it will not undergo this reaction in the space below d Enter the number of one of the compounds that will not undergo Nucleophilic Aromatic Substitution here e Explain...
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