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Is it likely that there are proteins that will not give a positive ninhydrin test? explain

Is it likely that there are proteins that will not give a positive ninhydrin test?

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Answer #1

Yes, proline and hydroxy proline doesn't give ninhydrin test.

This is because in nihydrin test , amino group undergoes the reaction and in proline and hydroxy proline , amino group is part of 5 membered ring and hence doesn't undergoes reaction.

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Is it likely that there are proteins that will not give a positive ninhydrin test? explain
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