Question

The adjoining illustration shows several oxygen-dissociation curves. Assuming that curve 3 corresponds to hemoglobin with physiological concentrations of CO₂ and 2.3-BPG at pH 7.0. Which of the curves represents each of the following perturbations?

a) Decrease in CO₂

n with physiological concentrations of CO, and 2.3-BPC the following perturbations? Saturation (Y) ро,

b) Increase in 2,3-BPG

c) Increase in pH

d) Loss of quaternary structure

Answer 1

Given Kata : -→ Saturation (Y) S Curve cui a por loss of quaternaxy stucture : Cla cking This type of curve is seen in case of myoglobin quaternary structure) Clive (2): An increase in pH, a decrease in con The dis sociation Curre shifts left if the amount Of Co2 decreases Cuive (3): no perturbation. It indicates to the heimal Oxygen discouation curve. Curve (4): An in crease in 2,3 - BPG. IF 2,3 - BPG level increases then the wygen dissociation curve shifts to the right.