Question

1.0 Identify the pH for each oxygen dissociation curve in the graph Active muscle Lungs Curve 1 0.8 Curve 1 Curve 2 0.6 Curve 2: Curve 3 0.4 Curve 3: 0.2 0 100 0 20 40 60 80 po2 (torr) 104 Data from R.E. Benesch and R. Benesch, 1974, Advances in Protein Chemistry 28: 211-37, doi:10.1016/S0065-3233(08)60231-4 The more reduced hemoglobin becomes, and the fewer O, What effect will hemoglobin have on the bicarbonate molecules it binds, the more readily it binds protons reaction in blood in the lungs? Conversely, the more oxygenated hemoglobin becomes, the more readily it releases protons It will decrease HCO3 production. It will increase the pH level. НЬ О,), + хн* ныо),-1 + О, It will decrease CO, production The bulk of CO, in the blood is transported as dissolved It will decrease the amount of O, unloaded. bicarbonate (HCO). Bicarbonate is formed via a reversible reaction catalyzed by carbonic anhydrase in red blood cells carbonic СО, + Н,О H2CO3H HCO3 anhvdrase y (fractional saturation) 91

Answer 1

(A)

curve 1 --- 4.6

curve 2 --- 7.4

curve 3 --- 7.2

(B) It will decrease the amount of oxygen unloaded