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points) Epigenetic changes, such as hypermethylation of DNA, can persist for how long? (4) (12 points) Name the neurotransmitter: NH2 HO NH2 HO ONH3 Seratonin
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(3) Epigenetic regulation of the genome by DNA methylation occur on nucleotide base cytosines, induce structural changes in the chromatin and lead to transcriptional changes of different genes. DNA methylation is often referred to as a lifelong inhibitory change that induces gene silencing the expression of memory suppressor genes. For example Huntington’s disease (HD) patients a number of genes, such as Sox2 and Pax6, were found to be hypermethylated, and to have accordingly reduced gene expression levels.

(4)

(5 points) Epigenetic changes, such as hypermethylation of DNA, can persist for how long? (4) (12 points) Name the neurotrans

но- NH2 но но Dopamine Anandamide NH2 HO но он OH NH2 Glutamic Acid Serotonin

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