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A woman with albinism (an X-linked recessive gene) has a child with a man who has...

A woman with albinism (an X-linked recessive gene) has a child with a man who has normal pigment. Their child has albinism with Klinefelter's syndrome (XXY). Where did the non-disjunction event occur?

a.Could only have occurred in the mother

b.Can't determine from the information given.

c.Could only have occurred in the father

d.Could have occurred in either the mother or the father

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Answer #1

the genotype of the child is XXY.

the child has 2 X chromosomes and the child has albinism. albinism is a sex-linked recessive trait, means the child lacks the normal allele, the father has normal allele and the mother has only the allele for albinism, so the child inherited X chromosomes from mother, 2 copies of the X chromosomes came from mother.

since the mother is homozygous recessive, non-disjunction in either meiosis I or meiosis II can result in XX gamete, which when ferilized with normal sperm carrying Y chromosome, can result in XXY child.

so the answer a) .Could only have occurred in the mother

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