Question

Simvastatin (marketed under the name Zorcord), is a medicine for high blood cholesterol levels, see structure below. Simvastatin belongs to the group of medicines called statins. Simvastatin acts by blocking an enzyme, HMG-CoA reductase, which is found in the cells where it is used in the cell's cholesterol production. This means that the cells production of cholesterol decreases. The cells then try to compensate for the decreased production by increasing the absorption of cholesterol from the blood. This in turn leads to decreased levels of cholesterol in the blood.

No explaination needed, just answers.

НО, (c) (d) -(b) a) What hybridization does carbon "b" have? -sp3d - sp -sp3 - sp2 - none of the above b) What type of carbon atom is "a" in Zorcord? -primary - secondary tertiary - quaternary - none of the above c) How many stereo centers are there in Zorcord? 3 -9 -7 -5 - none of the above

Answer 1

2 none (a) what hybridization does carbon (b) have ? - Sped – sp ,- 3p 3, -84 of the above Ans. -362 (6) What type of carbon atom (a) is in Zoncord? -primary, - secondary, - vertiary, -quatermary, - none of the above. Ans. tertiary carbon (e) How many stereo centers are there in Zomeond? -3 -9, -7, -5, - none of the above. 2 Ans. 9