Question

answer only part C

2. A study of allozymes in sockeye salmon examined 67 allozyme loci, and found 21 were polymorphic. Below is sample data from one of these loci, the sMDH allozyme locus. This genes has two alleles: A1 and B1, which can give three different genotypes (A1/A1, A1/B1; B1/B1). (2pts) S

MDH Phenotypes SMDH-A1/A1SMDH-A1/B1 SMDH-B1/B 99 Total # genotypes 48 212 

a) Calculate the observed genotype frequencies for the sMDH allozyme. 

b) Calculate the observed frequencies for the Al and B1 alleles. 

c) Calculate the expected frequency for each genotype, using Hardy-Weinberg equilibrium 

d) Is this population in Hardy-Weinberg equilibrium? Explain your answer

Answer 1

(c). According to Hardy-Weinberg principle-

At Hardy-Weinberg equilibrium-

Genotype frequency- \(p^{2}+2 p q+q^{2}=1\)

Allele frequency- \(p+q=1\)

Expected frequency for each genotype-

\(p^{2}(A 1)=99 \div 212=0.467\)

\(q^{2}(B 1)=65 \div 212=0.307\)

\(2 p q=48 \div 212=0.226\)