Question

B. Bonus (10 pts) Intramolecular Aldol... CH3

Answer 1

Answer.

In order to find out the final product, we need to follow the following steps:

Step-1: Identify the  - carbon

₁ and  ₂ are the  - carbons of the ketone group while  ' is the  - carbon of the aldehyde group.

With ring forming reactions, five and six membered rings are preferred and there is a possibility of ring formation if the attacking carbon is  ₂.

Step-2: An acid-base reaction

Hydroxide functions as a base and removes the acidic  - hydrogen bonded to the  - carbon and gives the reactive enolate.

Step-3: Nucleophilic attack