Question

Document1 - Word Tell me what you want to do Review View AaBbcc AaBbcc AaBb AaBbcc AaB AaBbce obce 1 Normal 1 No Spac.. Heading 1 Heading 2 Title Subtitle Subtle Em Paragraph Styles Which of these answers go to each questions (a) reducing cancer risks, (b) correcting/restoring cancer cells to normal, or (c) destroying cancerous tissue? 1. Molecular biologists have developed a new sequence of human genes called an ankyrin insulator sequence. A new corrected or therapeutic gene is placed within this sequence. Its role is to create an active area on a human chromosome where the new gene can work efficiently no matter what chromosome it lands on Tobacco smoking is the leading cause of preventable deaths worldwide. It is a risk factor for lung cancer and several other types of cancer. Results of analysis of the entire human gene collection (the "genome") support some previous findings that a region of human chromosome number 15 contains one or more genes that are associated with smoking intensity (the number of cigarettes smoked per day) and the closely related trait of nicotine dependency. Scanning people's genomes for these genes will help them to determine their risk of addiction should they begin smoking tobacco. 3. Virologists are modifying lentiviruses as vectors for carrying proto-oncogenes into cancer- transformed cells in culture. They are developing this virus for inserting the ras proto-oncogene directly into its correct location in the genome. The correct ras gene will already be linked to human DNA on either side of it and complexed with a recombination enzyme that will insert it into its correct location within the human genome. At the same time, the recombination enzyme will excise the defective oncogenic form of ras. The cells in culture should again come under normal hormonal control and require extra-cellular signals in order to continue dividing. म

Answer 1

1) b

The insertion of the new sequence into any chromosome would enable that cell even if has become cancerous, to carry on being a normal cell .this is possible due to the compensatory action of the newly inserted sequence.

2)a

Scanning of people's genomes would help in predicting the risks of being prone to cancer if at all they have started smoking. This would enable the individual to make judicial decision as to not even initiate smoking thus cutting down the risks of having cancer.

3)b

The excision of the defective oncogenic form of the ras gene and the replacement with the correct protooncogene would lead to restoring the cancerous cells back to normal cell .