Homework Answers
-OCH3 group attached with benzene ring is Ortho and para directing in nature.
The acyl group attack on the para position due greater steric repulsion on Ortho position.
Add Answer to:
Question 4 (10 pts) Each of the following compounds can be made with a Friedel-Crafts acylation....
Benzene underwent a Friedel-Crafts acylation reaction followed by a Clemmensen reduction. The product gave the 1H...
Benzene underwent a Friedel-Crafts acylation reaction followed
by a Clemmensen reduction. The product gave the 1H NMR
spectrum shown above. What acyl chloride was used in the
Friedel-Crafts acylation reaction? Hint: It would be helpful
if you first assign a structure to the compound shown in the
1H NMR spectrum.
Benzene underwent a Friedel-Crafts acylation reaction followed by a Clemmensen reduction. The product gave the 1H NMR spectrum shown above. What acyl chloride was used in the Friedel-Crafts acylation reaction?...
2. The following NMR was obtained from the product of a Friedel-Crafts acylation of an unknown...
2. The following NMR was obtained from the product of a Friedel-Crafts acylation of an unknown aromatic compound with acetyl chloride with aluminum chloride. Identify the product and the original aromatic compound from the NMR. ntegrals 2 2 PPM
Friedel-Crafts Acylation of Ferrocene "riedel-Crafts reactions are examples of electrophilic aromatic substitution reactions. The eaction involves...
Friedel-Crafts Acylation of Ferrocene "riedel-Crafts reactions are examples of electrophilic aromatic substitution reactions. The eaction involves the substitution of hydrogen on the aromatic ring system by an electrophilic arbon species forming a new carbon-carbon bond. Friedel-Crafts reactions may be used to ntroduce either an alkyl or acyl group. Ferrocene does not undergo addition reactions typical of cyclopentadiene, but undergoes Electrophilic aromatic substitution. The Friedel-Crafts acylation reaction of ferrocene involves he addition of the acylium cation to one of the carbon...
1. From what diene and dienophile could each of the following be made? (2 pts. each)...
1. From what diene and dienophile could each of the following be made? (2 pts. each) -NO₂ NO2 2. Starting from benzene, propose a step-by-step reaction sequence that would produce the following molecule (8 pts.) NO2 OH 3. What combination of acid chloride and arene would you chose to prepare each of the following compounds by Friedel-Crafts acylation? (2 pt. each)
Question 18 (4 points) Friedel-Crafts acylation reactions cannot be performed on aniline because: The amino group...
Question 18 (4 points) Friedel-Crafts acylation reactions cannot be performed on aniline because: The amino group gets acylated instead of the aromatic ring. The amino group attacks the Lewis acid to form an acid-base complex in which the aromatic ring is strongly deactivated. The amino group is strongly activating and multiple substitutions occur on the aromatic ring. The amino group is strongly deactivating preventing any substitution on the aromatic ring.
Chern 204-PSI, 6 . Friedel Crafts Acylation of an Unknown Benzene Compound (One weck lab The...
Chern 204-PSI, 6 . Friedel Crafts Acylation of an Unknown Benzene Compound (One weck lab The Intent of this Lab To acetylate an unknown benzene compound via a Friedel-Crafts acylation and use spectroscopic techniques to determine the acetophenone derivative's identity Introduction The Friedel-Crafts reaction dates back to before 1900 and it is still widely used today. The active electrophilic agent (an acylium ion) is classically prepared and reacts very quickly. Another appealing feature of this reaction is that the acylated...
in FRIEDEL-CRAFTS ACYLATION AND COLUMN CHROMATOGRAPHY lab (2 pts) Amount of acetyl chloride used ____4______(drops) (each...
in FRIEDEL-CRAFTS ACYLATION AND COLUMN CHROMATOGRAPHY lab
(2 pts) Amount of acetyl chloride used ____4______(drops) (each
drop is 0.01 mL) _____2______(equivalents) Based on the amount of
ferrocene you began the Friedel-Crafts reaction with, determine the
percent yield of acetylferrocene, diacetylferrocene, and the
percent recovery of unreacted ferrocene (show work)
react by 0.100 g of ferrocene at beginning
got 0 g of ferrocene, 0.012g of diacetylferrocene , 0.017g of
acetylferrocene
REACTION PROCEDURE: To a 5 mL conical vial, add a spin...
1. Draw Frost circle diagrams for each compound shown. Assume that all atoms in the ring...
1. Draw Frost circle diagrams for each compound shown. Assume that all atoms in the ring are sp? hybridized. Populate the pi electrons in the corresponding MO's. Identify the compound as aromatic or antiaromatic. (5 pts) Dec 2. What is the Hückel number of pi electrons for the molecule shown below? How many pi electron pairs does it have? Would you expect this molecule to be aromatic, antiaromatic or non aromatic? Explain. (3pts) 3. Rank the reactivity of the compounds...
The following questions are from an experiment titled Friedel-Crafts Alkylation for Organic Chemistry II Lab. There...
The following questions are from an experiment titled
Friedel-Crafts Alkylation for Organic Chemistry II Lab. There are
pictures attached of the lab manual.
2) Is this method a good route for the preparation of
p-sec-butyltoulene? Give reasons for your answer.
3) Why do you use a large excess of toulene. What are its
functions?
4) What is the purpose for adding the hydrochloric acid to the
water in the separatory funnel in step 5? Hint: If no acid is
added,...
4. Provide a plausible mechanism for the reaction shown. (6 pts) 7 NaNH. Hycor ND 5....
4. Provide a plausible mechanism for the reaction shown. (6 pts) 7 NaNH. Hycor ND 5. Each transformation shown below requires at least two steps. Provide the reagents/conditions for each transformation. (20 pts) Reagents Reagents A! Reagents D-7 Reagents Reagents 6. Predict the products from the Birch reductions shown below. (3 pts) Nz, NHU CH OH Bonus: (6 pts) Provide a synthesis for the target molecule using benzene. CO2H CO2H TM 1. Draw Frost circle diagrams for each compound shown....
Benzene underwent a Friedel-Crafts acylation reaction followed
by a Clemmensen reduction. The product gave the 1H NMR
spectrum shown above. What acyl chloride was used in the
Friedel-Crafts acylation reaction? Hint: It would be helpful
if you first assign a structure to the compound shown in the
1H NMR spectrum.
Benzene underwent a Friedel-Crafts acylation reaction followed by a Clemmensen reduction. The product gave the 1H NMR spectrum shown above. What acyl chloride was used in the Friedel-Crafts acylation reaction?...
2. The following NMR was obtained from the product of a Friedel-Crafts acylation of an unknown aromatic compound with acetyl chloride with aluminum chloride. Identify the product and the original aromatic compound from the NMR. ntegrals 2 2 PPM
Friedel-Crafts Acylation of Ferrocene "riedel-Crafts reactions are examples of electrophilic aromatic substitution reactions. The eaction involves the substitution of hydrogen on the aromatic ring system by an electrophilic arbon species forming a new carbon-carbon bond. Friedel-Crafts reactions may be used to ntroduce either an alkyl or acyl group. Ferrocene does not undergo addition reactions typical of cyclopentadiene, but undergoes Electrophilic aromatic substitution. The Friedel-Crafts acylation reaction of ferrocene involves he addition of the acylium cation to one of the carbon...
1. From what diene and dienophile could each of the following be made? (2 pts. each) -NO₂ NO2 2. Starting from benzene, propose a step-by-step reaction sequence that would produce the following molecule (8 pts.) NO2 OH 3. What combination of acid chloride and arene would you chose to prepare each of the following compounds by Friedel-Crafts acylation? (2 pt. each)
Question 18 (4 points) Friedel-Crafts acylation reactions cannot be performed on aniline because: The amino group gets acylated instead of the aromatic ring. The amino group attacks the Lewis acid to form an acid-base complex in which the aromatic ring is strongly deactivated. The amino group is strongly activating and multiple substitutions occur on the aromatic ring. The amino group is strongly deactivating preventing any substitution on the aromatic ring.
Chern 204-PSI, 6 . Friedel Crafts Acylation of an Unknown Benzene Compound (One weck lab The Intent of this Lab To acetylate an unknown benzene compound via a Friedel-Crafts acylation and use spectroscopic techniques to determine the acetophenone derivative's identity Introduction The Friedel-Crafts reaction dates back to before 1900 and it is still widely used today. The active electrophilic agent (an acylium ion) is classically prepared and reacts very quickly. Another appealing feature of this reaction is that the acylated...
in FRIEDEL-CRAFTS ACYLATION AND COLUMN CHROMATOGRAPHY lab
(2 pts) Amount of acetyl chloride used ____4______(drops) (each
drop is 0.01 mL) _____2______(equivalents) Based on the amount of
ferrocene you began the Friedel-Crafts reaction with, determine the
percent yield of acetylferrocene, diacetylferrocene, and the
percent recovery of unreacted ferrocene (show work)
react by 0.100 g of ferrocene at beginning
got 0 g of ferrocene, 0.012g of diacetylferrocene , 0.017g of
acetylferrocene
REACTION PROCEDURE: To a 5 mL conical vial, add a spin...
1. Draw Frost circle diagrams for each compound shown. Assume that all atoms in the ring are sp? hybridized. Populate the pi electrons in the corresponding MO's. Identify the compound as aromatic or antiaromatic. (5 pts) Dec 2. What is the Hückel number of pi electrons for the molecule shown below? How many pi electron pairs does it have? Would you expect this molecule to be aromatic, antiaromatic or non aromatic? Explain. (3pts) 3. Rank the reactivity of the compounds...
The following questions are from an experiment titled
Friedel-Crafts Alkylation for Organic Chemistry II Lab. There are
pictures attached of the lab manual.
2) Is this method a good route for the preparation of
p-sec-butyltoulene? Give reasons for your answer.
3) Why do you use a large excess of toulene. What are its
functions?
4) What is the purpose for adding the hydrochloric acid to the
water in the separatory funnel in step 5? Hint: If no acid is
added,...
4. Provide a plausible mechanism for the reaction shown. (6 pts) 7 NaNH. Hycor ND 5. Each transformation shown below requires at least two steps. Provide the reagents/conditions for each transformation. (20 pts) Reagents Reagents A! Reagents D-7 Reagents Reagents 6. Predict the products from the Birch reductions shown below. (3 pts) Nz, NHU CH OH Bonus: (6 pts) Provide a synthesis for the target molecule using benzene. CO2H CO2H TM 1. Draw Frost circle diagrams for each compound shown....
Most questions answered within 3 hours.
-
The patient recovery time from a particular surgical procedure
is normally distributed with a mean of...
asked 2 minutes from now -
Python Program: Design the logic for and implement a program
that merges the two files into...
asked 13 minutes ago -
Human relations refer to the way a company arranges people,
jobs, and communications so that work...
asked 14 minutes ago -
The specific radiocarbon activity of a sample of wood is 6.25
gms dpm/gm of carbon. The...
asked 18 minutes ago -
An aqueous magnesium chloride solution is made by dissolving
6.96 moles of MgCl2 in sufficient water...
asked 20 minutes ago -
Ken believes the average age of men who come to get a haircut at
his barber...
asked 42 minutes ago -
(Ratio Analysis): Last year Co. XYZ had sales of $ 400,000, with
“cost of goods sold”...
asked 51 minutes ago -
can someone please write the balanced chemical
equation for the synthesis of Bromoacetanilide
from;
aniline +...
asked 47 minutes ago -
1. If a corporation purchases land and building and subsequently
tears down the building and uses...
asked 58 minutes ago -
Consider a 23-year bond with 7 percent annual coupon payments.
The market rate (YTM) is 6.4...
asked 1 hour ago -
a tuba creates a 4th harmonic of frequency 116.5 Hz. what is the
frequency of the...
asked 1 hour ago -
A coconut mass 2kg falls from a 30m tall tree. The coconut falls
and comes to...
asked 1 hour ago