LILIT OH O Но Ethylene oxide is the starting material for the synthesis of 1,4-dioxane. Write...
Ethylene oxide is the starting material for the synthesis of 1, 4-dioxane. Write a detailed mechanism for this synthesis (shown above). Then draw curved arrows that depict electron reorganization for Step 2 of the mechanism shown below. Unless specified otherwise, do not count proton transfers when counting steps. The starting materials of this step are provided.
HO OH ОН Ethylene oxide is the starting material for the synthesis of 1,4-dioxepane. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions :o: Hö: H-OH :0:
Write a detailed mechanism for the reaction of dimethylamine in water with acetic anhydride to create N,N-dimethylacetamide which proceeds in 3 steps including proton transfer steps. Then draw curved arrows that depict electron reorganization for the mechanism step below. Arrow-pushing Instructions nno XT :0: :0 H CH3 :N-Me 1 нс N-Me Me Me
H3C Нас H3C CO2H Br 1. NaOH, H20 2 HJo Write a detailed mechanism for the Favorski rearrangement (shown above) which proceeds in two steps followed by a proton transfer. Then draw curved arrows that depict electron reorganization for the mechanism step below Arrow-pushing Instructions IIn OOH H3C H3C Br. :O-H
Write a detailed mechanism for the reaction shown above which proceeds in six steps including proton transfer steps. Then draw curved arrows that depict electron reorganization for the mechanism step below.
1) Outline a synthesis for the product shown below from the given starting material. OH CN 2) Provide an arrow-pushing mechanism for each of the transformations shown below. HBr H2SO4 H20
Draw a structural formula for the product of the aldol reaction of the compound shown above, as well as the a.B-unsaturated aldehyde or ketone formed from dehydration of the aldol product. You do not have to consider stereochemistry. You do not have to explicitly draw H atoms. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right comer. Separate structures using the sign from the drop-down menu. . o 1. Og 2. (CH3)2...
Experiment Questions What is an epoxide and how is it useful with respect to synthesis design? • What are typical reagents used for epoxidation? • What is the mechanism for epoxidation? Must stereospecificity be considered? Experiment Techniques • Use of sodium bisulfite wash to remove excess peroxy acid from reaction mixture. Introduction By now you are well aware that the product of previous experiment (reaction of cyclohexanol and acid) is an alkene. You should also be storing key reactions of...